PMID- 21792544
OWN - NLM
STAT- MEDLINE
DCOM- 20120126
LR  - 20211020
IS  - 1534-312X (Electronic)
IS  - 1522-8037 (Linking)
VI  - 13
IP  - 5
DP  - 2011 Oct
TI  - Differentiating food allergies from food intolerances.
PG  - 426-34
LID - 10.1007/s11894-011-0215-7 [doi]
AB  - Adverse reactions to foods are extremely common, and generally they are 
      attributed to allergy. However, clinical manifestations of various degrees of 
      severity related to ingestion of foods can arise as a result of a number of 
      disorders, only some of which can be defined as allergic, implying an immune 
      mechanism. Recent epidemiological data in North America showed that the 
      prevalence of food allergy in children has increased. The most common food 
      allergens in the United States include egg, milk, peanut, tree nuts, wheat, 
      crustacean shellfish, and soy. This review examines the various forms of food 
      intolerances (immunoglobulin E [IgE] and non-IgE mediated), including celiac 
      disease and gluten sensitivity. Immune mediated reactions can be either IgE 
      mediated or non-IgE mediated. Among the first group, Immediate GI 
      hypersensitivity and oral allergy syndrome are the best described. Often, but not 
      always, IgE-mediated food allergies are entities such as eosinophilic esophagitis 
      and eosinophilic gastroenteropathy. Non IgE-mediated immune mediated food 
      reactions include celiac disease and gluten sensitivity, two increasingly 
      recognized disorders. Finally, non-immune mediated reactions encompass different 
      categories such as disorders of digestion and absorption, inborn errors of 
      metabolism, as well as pharmacological and toxic reactions.
FAU - Guandalini, Stefano
AU  - Guandalini S
AD  - Section of Pediatric Gastroenterology, Celiac Disease Center, University of 
      Chicago, 5839 S. Maryland Ave, MC 4065, Chicago, IL 60637, USA. 
      sguandalini@peds.bsd.uchicago.edu
FAU - Newland, Catherine
AU  - Newland C
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Gastroenterol Rep
JT  - Current gastroenterology reports
JID - 100888896
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Food/*adverse effects
MH  - Food Hypersensitivity/*diagnosis/immunology
MH  - Gastrointestinal Diseases/*diagnosis/etiology
MH  - Humans
MH  - Immunoglobulin E
EDAT- 2011/07/28 06:00
MHDA- 2012/01/27 06:00
CRDT- 2011/07/28 06:00
PHST- 2011/07/28 06:00 [entrez]
PHST- 2011/07/28 06:00 [pubmed]
PHST- 2012/01/27 06:00 [medline]
AID - 10.1007/s11894-011-0215-7 [doi]
PST - ppublish
SO  - Curr Gastroenterol Rep. 2011 Oct;13(5):426-34. doi: 10.1007/s11894-011-0215-7.