PMID- 21794615
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110728
IS  - 1885-1398 (Electronic)
IS  - 1699-258X (Linking)
VI  - 5
IP  - 5
DP  - 2009 Sep-Oct
TI  - [From bone marrow edema to osteonecrosis. New concepts].
PG  - 223-7
LID - 10.1016/j.reuma.2008.02.004 [doi]
AB  - The widespread use of MRI in the diagnosis of articular pathology has allowed for 
      an improved knowledge of a series of disturbances that occur with epiphyseal bone 
      edema as a main radiological sign, featured as low signal intensity of the bone 
      marrow on T1 and high signal on STIR and fat saturated T2 sequences. The new 
      etiopathogenic theories postulate a clear differentiation between primary and 
      secondary osteonecrosis. While secondary osteonecrosis is related to risk 
      factors, primary osteonecrosis is a result of a subcondral insufficiency 
      fracture. Both have different characteristic and MRI criteria. The pathogenesis 
      of transient bone edema syndrome (BMES) is currently under discussion, divided 
      between the biomechanic theory and the more classic one that relates to the 
      complex and poorly understood mechanisms associated with complex regional pain 
      syndrome type I (reflex sympathetic dystrophy). The BMES, classically considered 
      a reversible form of osteonecrosis, has enough differentiated features to be 
      considered as a distinct disease. Bone marrow edema can be as extensive in either 
      insufficiency or fatigue stress fractures than in BMES. The diagnostic key is the 
      display of a subcondral bone fracture. These can be resolved or occasionally 
      evolve into a primary osteonecrosis.
CI  - Copyright (c) 2008 Elsevier Espana, S.L. All rights reserved.
FAU - Fernandez-Canton, Guillermo
AU  - Fernandez-Canton G
AD  - Centro OSATEK, Unidad de Dr. Areilza, Bilbao, Pais Vasco, Espana.
LA  - spa
PT  - English Abstract
PT  - Journal Article
TT  - Del edema de medula osea a la osteonecrosis. Nuevos conceptos.
DEP - 20090520
PL  - Spain
TA  - Reumatol Clin
JT  - Reumatologia clinica
JID - 101293923
EDAT- 2009/09/01 00:00
MHDA- 2009/09/01 00:01
CRDT- 2011/07/29 06:00
PHST- 2008/02/05 00:00 [received]
PHST- 2008/02/09 00:00 [accepted]
PHST- 2011/07/29 06:00 [entrez]
PHST- 2009/09/01 00:00 [pubmed]
PHST- 2009/09/01 00:01 [medline]
AID - S1699-258X(09)00064-3 [pii]
AID - 10.1016/j.reuma.2008.02.004 [doi]
PST - ppublish
SO  - Reumatol Clin. 2009 Sep-Oct;5(5):223-7. doi: 10.1016/j.reuma.2008.02.004. Epub 
      2009 May 20.