PMID- 21797024
OWN - NLM
STAT- MEDLINE
DCOM- 20110823
LR  - 20190729
IS  - 1060-3271 (Print)
IS  - 1060-3271 (Linking)
VI  - 94
IP  - 3
DP  - 2011 May-Jun
TI  - Validation of a method for arsenic speciation in food by ion 
      chromatography-inductively coupled plasma/mass spectrometry after 
      ultrasonic-assisted enzymatic extraction.
PG  - 947-58
AB  - A fully validated and rapid quantitative method is presented for determination of 
      inorganic arsenic [arsenite, As(III) and arsenate, As(V)] and organic arsenic 
      species (methylarsonic acid, dimethylarsinic acid, and arsenobetaine) by ion 
      chromatography paired with inductively coupled plasma/MS after 
      ultrasonic-assisted enzymatic extraction (UAEE) in rice- and seafood-based raw 
      materials and finished products. This method gives toxicological meaning to 
      arsenic analysis, since the sum of the toxic chemical forms As(III) and As(V) can 
      be determined. In contrast to classical water-methanol extraction, UAEE enables 
      drastic acceleration of sample extraction (5 min instead of several hours), while 
      total arsenic extraction efficiency is improved without species conversion. 
      Validation was performed to evaluate the method for selectivity, linearity, 
      LOD/LOQ (0.007-0.020 mg/kg), trueness, precision (HorRat values, 0.2-0.6), 
      recovery (93-122%), and uncertainty. The method was also satisfactorily tested 
      using two proficiency tests. Performance characteristics are reported for four 
      certified reference materials, standard reference material (SRM) 1568a (rice 
      flour), Institute for Reference Materials and Measurements 804 (rice flour), SRM 
      2976 (mussel tissue), certified reference material-627 (tuna fish), and several 
      commercial food samples populating five AOAC triangle food sectors. The results 
      indicated that this speciation method is cost-efficient, time-saving, and 
      accurate, as well as fit-for-purpose, according to International Organization for 
      Standardization/International Electrotechnical Commission 17025:2005 standard, 
      and could be used for routine analysis.
FAU - Dufailly, Vincent
AU  - Dufailly V
AD  - Nestle Research Center, Vers-Chez-Les-Blanc, CH-1000 Lausanne 26, Switzerland.
FAU - Nicolas, Marine
AU  - Nicolas M
FAU - Richoz-Payot, Janique
AU  - Richoz-Payot J
FAU - Poitevin, Eric
AU  - Poitevin E
LA  - eng
PT  - Journal Article
PL  - England
TA  - J AOAC Int
JT  - Journal of AOAC International
JID - 9215446
RN  - 0 (Environmental Pollutants)
RN  - N712M78A8G (Arsenic)
SB  - IM
MH  - Animals
MH  - Arsenic/*chemistry
MH  - Bivalvia/chemistry
MH  - Chromatography/*methods
MH  - Crustacea/chemistry
MH  - Environmental Pollutants/chemistry
MH  - Food Analysis/*methods
MH  - Humans
MH  - Infant
MH  - Infant Food/analysis
MH  - Mass Spectrometry/*methods
MH  - Milk/chemistry
MH  - Muscle, Skeletal/chemistry
MH  - Oryza/chemistry
MH  - Reproducibility of Results
MH  - Soy Foods/analysis
MH  - Tuna
MH  - Ultrasonics
EDAT- 2011/07/30 06:00
MHDA- 2011/08/24 06:00
CRDT- 2011/07/30 06:00
PHST- 2011/07/30 06:00 [entrez]
PHST- 2011/07/30 06:00 [pubmed]
PHST- 2011/08/24 06:00 [medline]
PST - ppublish
SO  - J AOAC Int. 2011 May-Jun;94(3):947-58.