PMID- 21797142 OWN - NLM STAT- MEDLINE DCOM- 20110818 LR - 20111117 IS - 0031-2983 (Print) IS - 0031-2983 (Linking) VI - 103 IP - 2 DP - 2011 Apr TI - Subcutaneous Ewing sarcoma/PNET as a second cancer in a previously irradiated young patient. an uncommon type of post-irradiation soft tissue sarcoma. PG - 43-5 AB - Soft tissue sarcomas account for a small proportion of second cancers, with an estimated frequency of < 10%. The most common histologic type of soft tissue sarcomas as second cancers include mostly high-grade sarcomas, such as rhabdomyosarcoma, malignant peripheral nerve sheath tumour, fibrosarcoma, leiomyosarcoma, synovial sarcoma, alveolar soft part sarcoma and Ewing sarcoma/primitive neuroectodermal tumour (PNET). We report a case of superficial soft tissue Ewing sarcoma/PNET as a second cancer in a young patient previously treated for Hodgkin's disease (HD). To the best of our knowledge and based on a literature search, this is the first reported case of post-irradiation soft tissue Ewing sarcoma/PNET as a second cancer arising in the same area irradiated for cure of HD. FAU - Bruno, M AU - Bruno M AD - Division Anatomic Pathology, Madonna delle Grazie Hospital, Matera, Italy. FAU - D'antona, G I AU - D'antona GI FAU - Vita, G AU - Vita G FAU - Perrone, G AU - Perrone G FAU - Fiordelisi, F AU - Fiordelisi F FAU - Bisceglia, M AU - Bisceglia M LA - eng PT - Case Reports PT - Journal Article PT - Review PL - Italy TA - Pathologica JT - Pathologica JID - 0401123 SB - IM MH - Adolescent MH - Combined Modality Therapy MH - Hodgkin Disease/*radiotherapy MH - Humans MH - Male MH - Neoplasms, Second Primary/*diagnosis/pathology/therapy MH - Sarcoma, Ewing/*diagnosis/pathology/therapy MH - Soft Tissue Neoplasms/*diagnosis/pathology/therapy MH - Subcutaneous Tissue/*pathology MH - Treatment Outcome EDAT- 2011/07/30 06:00 MHDA- 2011/08/19 06:00 CRDT- 2011/07/30 06:00 PHST- 2011/07/30 06:00 [entrez] PHST- 2011/07/30 06:00 [pubmed] PHST- 2011/08/19 06:00 [medline] PST - ppublish SO - Pathologica. 2011 Apr;103(2):43-5.