PMID- 21804938
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20111110
LR  - 20211020
IS  - 2090-1259 (Electronic)
IS  - 2090-1240 (Print)
IS  - 2090-1240 (Linking)
VI  - 2011
DP  - 2011
TI  - Graves' Disease as a Manifestation of Immune Reconstitution in HIV-Infected 
      Individuals after Initiation of Highly Active Antiretroviral Therapy.
PG  - 743597
LID - 10.1155/2011/743597 [doi]
LID - 743597
AB  - Graves' disease after the initiation of highly active antiretroviral therapy 
      (HAART) in certain HIV-1-infected individuals has been described as an immune 
      reconstitution inflammatory syndrome (IRIS). This phenomenon should be suspected 
      in individuals who present with clinical deterioration and a presentation 
      suggestive of hyperthyroidism despite good virological and immunological response 
      to HAART. Signs and symptoms of hyperthyroidism may be discrete or overt and 
      typically develop 8-33 months after initiating therapy. One to two percent of 
      HIV-infected patients can present with overt thyroid disease. Relatively few 
      cases of Graves' IRIS have been reported in the literature to date. We describe 
      four cases of Graves' IRIS in HIV-infected patients who were started on HAART 
      therapy.
FAU - Rasul, Samad
AU  - Rasul S
AD  - Division of Infectious Diseases, Department of Internal Medicine, Howard 
      University Hospital, Washington DC, USA.
FAU - Delapenha, Robert
AU  - Delapenha R
FAU - Farhat, Faria
AU  - Farhat F
FAU - Gajjala, Jhansi
AU  - Gajjala J
FAU - Zahra, Syeda Mehreen
AU  - Zahra SM
LA  - eng
PT  - Case Reports
DEP - 20110725
PL  - United States
TA  - AIDS Res Treat
JT  - AIDS research and treatment
JID - 101553816
PMC - PMC3144671
EDAT- 2011/08/02 06:00
MHDA- 2011/08/02 06:01
PMCR- 2011/07/25
CRDT- 2011/08/02 06:00
PHST- 2011/01/31 00:00 [received]
PHST- 2011/05/10 00:00 [accepted]
PHST- 2011/08/02 06:00 [entrez]
PHST- 2011/08/02 06:00 [pubmed]
PHST- 2011/08/02 06:01 [medline]
PHST- 2011/07/25 00:00 [pmc-release]
AID - 10.1155/2011/743597 [doi]
PST - ppublish
SO  - AIDS Res Treat. 2011;2011:743597. doi: 10.1155/2011/743597. Epub 2011 Jul 25.