PMID- 21805615
OWN - NLM
STAT- MEDLINE
DCOM- 20140220
LR  - 20130723
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 82
IP  - 2
DP  - 2013 Aug 1
TI  - Differential 1-year clinical outcomes for ST-segment elevation myocardial 
      infarction related to stent thrombosis or saphenous vein graft thrombosis.
PG  - 193-200
LID - 10.1002/ccd.23300 [doi]
AB  - AIM: Thrombosis of stents and of saphenous vein grafts (SVG) remains a severe 
      complication of either revascularization techniques that often are present as ST 
      elevation myocardial infarction (STEMI). The aim of this longitudinal cohort 
      study was to compare the 1-year clinical outcomes among STEMI patients requiring 
      primary PCI due to stent thrombosis and graft occlusion presenting with STEMI. 
      METHODS AND RESULTS: We prospectively collected data on all patients undergoing 
      primary PCI at the Montreal Heart Institute between April 1, 2007 and March 30, 
      2008. Study patients were grouped according to the etiology of the STEMI: stent 
      thrombosis, graft thrombosis, or atherosclerosis-related STEMIs (control group). 
      The primary combined end-point, major adverse cardiac events (MACE), was defined 
      as death, myocardial infarction, and target vessel revascularization within 12 
      months as primary end point. Of the 489 STEMI patients included in the study, 23 
      were due to stent thrombosis, 22 to graft thrombosis, and 444 in the control 
      group. Stent and graft thromboses were associated with a higher MACE rates, 26.1 
      and 22.7%, respectively, compared to the control group, 9.3% (P = 0.004). 
      Moreover, only stent thrombosis was associated with an increased risk of MACE (HR 
      2.57, confidence interval 95% 1.08-6.08. CONCLUSION: Patients with stent 
      thrombosis present with higher rate of reinfarction while graft thrombosis is 
      associated with an increase in 1-year cardiac mortality. Using multivariate 
      analysis, higher MACE rates were associated with stent thrombosis as compared to 
      graft thrombosis.
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Arzamendi, Dabit
AU  - Arzamendi D
AD  - Interventional Cardiology Division, Department of Medicine, Montreal Heart 
      Institute, Universite de Montreal, Montreal, Qc H1T 1C8, Canada.
FAU - Ly, Hung Q
AU  - Ly HQ
FAU - Tanguay, Jean-Francois
AU  - Tanguay JF
FAU - Armero, Sebastien
AU  - Armero S
FAU - Jilaihawi, Hasan
AU  - Jilaihawi H
FAU - Gallo, Richard
AU  - Gallo R
FAU - Ibrahim, Reda
AU  - Ibrahim R
FAU - L'Allier, Philippe
AU  - L'Allier P
FAU - Blondeau, Lucie
AU  - Blondeau L
FAU - Gosselin, Gilbert
AU  - Gosselin G
FAU - Gregoire, Jean
AU  - Gregoire J
FAU - Doucet, Serge
AU  - Doucet S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20130507
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
CIN - Catheter Cardiovasc Interv. 2013 Aug 1;82(2):201-2. PMID: 23878031
MH  - Aged
MH  - Chi-Square Distribution
MH  - Coronary Artery Bypass/*adverse effects/mortality
MH  - Coronary Thrombosis/*etiology/mortality/physiopathology/therapy
MH  - Female
MH  - Graft Occlusion, Vascular/*etiology/mortality/physiopathology/therapy
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Myocardial Infarction/diagnosis/mortality/surgery/*therapy
MH  - Percutaneous Coronary Intervention/*adverse effects/*instrumentation/mortality
MH  - Proportional Hazards Models
MH  - Prospective Studies
MH  - Quebec
MH  - Recurrence
MH  - Registries
MH  - Risk Factors
MH  - Saphenous Vein/physiopathology/*transplantation
MH  - *Stents
MH  - Time Factors
MH  - Treatment Outcome
MH  - Vascular Patency
MH  - Venous Thrombosis/*etiology/mortality/physiopathology/therapy
OTO - NOTNLM
OT  - major adverse cardiac events
OT  - myocardial infarction
OT  - stent thrombosis
OT  - venous graft thrombosis
EDAT- 2011/08/02 06:00
MHDA- 2014/02/22 06:00
CRDT- 2011/08/02 06:00
PHST- 2010/12/29 00:00 [received]
PHST- 2011/06/27 00:00 [accepted]
PHST- 2011/08/02 06:00 [entrez]
PHST- 2011/08/02 06:00 [pubmed]
PHST- 2014/02/22 06:00 [medline]
AID - 10.1002/ccd.23300 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2013 Aug 1;82(2):193-200. doi: 10.1002/ccd.23300. 
      Epub 2013 May 7.