PMID- 2180999
OWN - NLM
STAT- MEDLINE
DCOM- 19900504
LR  - 20220331
IS  - 0303-6987 (Print)
IS  - 0303-6987 (Linking)
VI  - 17
IP  - 1
DP  - 1990 Feb
TI  - Characterization of the dermal infiltrates in Jessner's lymphocytic infiltrate of 
      the skin, polymorphous light eruption and cutaneous lupus erythematosus: 
      differential diagnostic and pathogenetic aspects.
PG  - 2-8
AB  - In the present study a comparative immunohistochemical study was performed on 
      skin biopsies from of patients with Jessner's lymphocytic infiltration of the 
      skin (LIS), polymorphous light eruption (PLE), discoid lupus erythematosus (DLE) 
      and subacute cutaneous lupus erythematosus (SCLE) using a large panel of 
      monoclonal antibodies against T cell differentiation antigens (CD3, CD4, CD8), 
      immunoregulatory T cell subsets (CD7, 4B4, 2H4, Leu 8), B cells (CD22), activated 
      cells CD25, OKT9, HLA-DR), Langerhans cells (CD1) and macrophages (Leu-M5). The 
      results showed many similarities between LIS and PLE. The most important 
      differences between these conditions and CDLE/SCLE were the high proportions of 
      cells reactive with monoclonal antibody Leu-8 and the absence of T cells 
      expressing HLA-DR antigens in LIS and PLE, suggesting absence of local T cell 
      activation in these conditions. The differential diagnostic and pathogenetic 
      aspects of these findings will be discussed.
FAU - Rijlaarsdam, J U
AU  - Rijlaarsdam JU
AD  - Department of Dermatology, Free University Hospital, Amsterdam, The Netherlands.
FAU - Nieboer, C
AU  - Nieboer C
FAU - de Vries, E
AU  - de Vries E
FAU - Willemze, R
AU  - Willemze R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cutan Pathol
JT  - Journal of cutaneous pathology
JID - 0425124
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Antigens, Differentiation)
RN  - 0 (Antigens, Differentiation, T-Lymphocyte)
RN  - 0 (HLA-DR Antigens)
SB  - IM
MH  - Antibodies, Monoclonal
MH  - Antigens, Differentiation/analysis
MH  - Antigens, Differentiation, T-Lymphocyte/analysis
MH  - Biopsy
MH  - Diagnosis, Differential
MH  - HLA-DR Antigens/analysis
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*pathology
MH  - Lymphocytes/*pathology
MH  - Skin/*pathology
MH  - Skin Diseases, Vesiculobullous/*pathology
EDAT- 1990/02/01 00:00
MHDA- 1990/02/01 00:01
CRDT- 1990/02/01 00:00
PHST- 1990/02/01 00:00 [pubmed]
PHST- 1990/02/01 00:01 [medline]
PHST- 1990/02/01 00:00 [entrez]
AID - 10.1111/j.1600-0560.1990.tb01670.x [doi]
PST - ppublish
SO  - J Cutan Pathol. 1990 Feb;17(1):2-8. doi: 10.1111/j.1600-0560.1990.tb01670.x.