PMID- 21812266
OWN - NLM
STAT- MEDLINE
DCOM- 20130307
LR  - 20161018
IS  - 1003-5370 (Print)
IS  - 1003-5370 (Linking)
VI  - 31
IP  - 5
DP  - 2011 May
TI  - [Clinical study of curing patients with perennial allergic rhinitis by qumin 
      tongbi nasal spraying agent].
PG  - 643-6
AB  - OBJECTIVE: To study the mechanism of action and the therapeutic efficacy of 
      treating patients with perennial allergic rhinitis by Qumin Tongbi Nasal Spraying 
      Agent (QTNSA). METHODS: One hundred and three patients with perennial allergic 
      rhinitis were randomly assigned to two groups. Of them, 57 patients in the 
      treatment group were treated with QTNSA and 46 patients in the control group were 
      treated with Veconase. Seven days were taken as one therapeutic course, two 
      courses in total. The therapeutic efficacy and the serum levels of interleukin-4 
      (IL-4), IL-8, immunoglobulin E (IgE) and nasal airway resistance (NAR), symptoms 
      and signs integrals before and after treatment were observed in the two groups. 
      RESULTS: There was no statistical significance between the treatment group and 
      the control group in the markedly effective rate (61.40% vs. 63. 04%) and the 
      total effective rate (87.72% vs. 89.13%). After treatment symptoms and signs 
      integrals of the two groups were significantly improved when compared with before 
      treatment (P < 0.01). There was no significant difference between the two groups 
      after treatment (P > 0.05). The serum levels of IL-4, IL-8, IgE, and NAR were 
      significantly higher in the two groups than those of the normal group. They 
      significantly decreased after treatment in the two groups, showing statistical 
      difference (P < 0.01). There was no statistical difference between the treatment 
      group and the control group (P > 0.05). CONCLUSIONS: QTNSA could effectively 
      treat perennial allergic rhinitis. It could obviously lower serum levels of IL-4, 
      IL-8, IgE, and NAR in patients with perennial allergic rhinitis.
FAU - Chen, Xin-xin
AU  - Chen XX
AD  - Department of Otorhinolaryngology, Zhuhai Hospital of Guangdong Provincial 
      Traditional Chinese Medicine Hospital, Zhuhai. xin32838@126.com
FAU - Fu, Ji-xiong
AU  - Fu JX
FAU - Huang, Jian
AU  - Huang J
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - China
TA  - Zhongguo Zhong Xi Yi Jie He Za Zhi
JT  - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese 
      journal of integrated traditional and Western medicine
JID - 9211576
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Interleukin-8)
RN  - 0 (Nasal Sprays)
RN  - 207137-56-2 (Interleukin-4)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Drugs, Chinese Herbal/administration & dosage/*therapeutic use
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Interleukin-4/blood
MH  - Interleukin-8/blood
MH  - Male
MH  - Middle Aged
MH  - Nasal Sprays
MH  - *Phytotherapy
MH  - Rhinitis, Allergic, Perennial/blood/*drug therapy
MH  - Young Adult
EDAT- 2011/08/05 06:00
MHDA- 2013/03/08 06:00
CRDT- 2011/08/05 06:00
PHST- 2011/08/05 06:00 [entrez]
PHST- 2011/08/05 06:00 [pubmed]
PHST- 2013/03/08 06:00 [medline]
PST - ppublish
SO  - Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 May;31(5):643-6.