PMID- 21813014 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20111110 LR - 20211020 IS - 1756-0500 (Electronic) IS - 1756-0500 (Linking) VI - 4 DP - 2011 Aug 3 TI - Indirect calibration between clinical observers - application to the New York Heart Association functional classification system. PG - 276 LID - 10.1186/1756-0500-4-276 [doi] AB - BACKGROUND: Previous studies showed an inter-observer agreement for the NYHA classification of approximately 55%. The aim of this study was to calibrate the New York Heart Association (NYHA) classification system between observers, increasing its reliability. RESULTS: Among 1136 community-dwellers in Porto, Portugal, aged >/= 45 years, 265 reporting breathlessness answered a 4-item questionnaire to characterize symptom severity. The questionnaire was administered by 7 physicians who also classified the subject's functional capacity according to NYHA. Each subject was assessed by one physician. We calibrated NYHA classifications by the concurrent method, using 1-parameter logistic graded response model. Discrepancies between observers were assessed by differences in ability thresholds between NYHA classes I-II and II-III. The ability estimated by the model was used to predict the NYHA classification for each observer.Estimates of the first and second thresholds for each observer ranged from -1.92 to 0.46 and from 1.42 to 2.30, respectively. The agreement between estimated ability and the observers' NYHA classification was 88% (kappa = 0.61). CONCLUSIONS: The study objectively indicates the main reason why several studies have reported low inter-observer is the existence of discrepant thresholds between observers in the definition of NYHA classes. The concurrent method can be used to minimize the reliability problem of NYHA classification. FAU - Severo, Milton AU - Severo M AD - Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal. milton@med.up.pt. FAU - Gaio, Rita AU - Gaio R FAU - Lourenco, Patricia AU - Lourenco P FAU - Alvelos, Margarida AU - Alvelos M FAU - Bettencourt, Paulo AU - Bettencourt P FAU - Azevedo, Ana AU - Azevedo A LA - eng PT - Journal Article DEP - 20110803 PL - England TA - BMC Res Notes JT - BMC research notes JID - 101462768 PMC - PMC3160980 EDAT- 2011/08/05 06:00 MHDA- 2011/08/05 06:01 PMCR- 2011/08/03 CRDT- 2011/08/05 06:00 PHST- 2011/06/14 00:00 [received] PHST- 2011/08/03 00:00 [accepted] PHST- 2011/08/05 06:00 [entrez] PHST- 2011/08/05 06:00 [pubmed] PHST- 2011/08/05 06:01 [medline] PHST- 2011/08/03 00:00 [pmc-release] AID - 1756-0500-4-276 [pii] AID - 10.1186/1756-0500-4-276 [doi] PST - epublish SO - BMC Res Notes. 2011 Aug 3;4:276. doi: 10.1186/1756-0500-4-276.