PMID- 21820205
OWN - NLM
STAT- MEDLINE
DCOM- 20120207
LR  - 20131121
IS  - 1097-6787 (Electronic)
IS  - 0190-9622 (Linking)
VI  - 66
IP  - 1
DP  - 2012 Jan
TI  - Peanut allergy: an increasingly common life-threatening disorder.
PG  - 136-43
LID - 10.1016/j.jaad.2011.02.031 [doi]
AB  - Allergic reactions to peanuts in children have become a significant medical and 
      legal concern worldwide, with a rising incidence of this potentially fatal 
      condition. Peanut allergy represents an immunoglobulin E (IgE)-mediated 
      hypersensitivity reaction to peanut proteins and is responsible for the majority 
      of cases of food-induced anaphylaxis. Even trace quantities of peanut in a 
      sensitized individual can be fatal, with rapid onset of symptoms often including 
      the cutaneous findings of urticaria, angioedema, or a diffuse nonspecific 
      dermatitis. Peanut allergy is usually a lifelong condition, since only about 20% 
      of affected individuals outgrow it. Some schools ban peanut butter and jelly 
      sandwiches, once a common dietary option, as fear of medical and legal 
      consequences is escalating. Children with peanut allergy and their families 
      should be knowledgeable about management strategies, including carrying and 
      properly administering self-injectable epinephrine. New immunotherapeutic options 
      are being investigated and appear promising.
CI  - Copyright (c) 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. 
      All rights reserved.
FAU - Husain, Zain
AU  - Husain Z
AD  - Dermatology, Preventive Medicine and Community Health, Pediatrics, Medicine, and 
      Pathology, New Jersey Medical School, Newark, New Jersey 07103-2714, USA.
FAU - Schwartz, Robert A
AU  - Schwartz RA
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20110804
PL  - United States
TA  - J Am Acad Dermatol
JT  - Journal of the American Academy of Dermatology
JID - 7907132
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Anaphylaxis/diagnosis/etiology
MH  - Child
MH  - Child, Preschool
MH  - Epinephrine/administration & dosage
MH  - Humans
MH  - Immunologic Tests
MH  - *Peanut Hypersensitivity/diagnosis/epidemiology/immunology/therapy
MH  - Prevalence
MH  - United States/epidemiology
EDAT- 2011/08/09 06:00
MHDA- 2012/02/09 06:00
CRDT- 2011/08/09 06:00
PHST- 2010/08/23 00:00 [received]
PHST- 2011/02/13 00:00 [revised]
PHST- 2011/02/17 00:00 [accepted]
PHST- 2011/08/09 06:00 [entrez]
PHST- 2011/08/09 06:00 [pubmed]
PHST- 2012/02/09 06:00 [medline]
AID - S0190-9622(11)00317-3 [pii]
AID - 10.1016/j.jaad.2011.02.031 [doi]
PST - ppublish
SO  - J Am Acad Dermatol. 2012 Jan;66(1):136-43. doi: 10.1016/j.jaad.2011.02.031. Epub 
      2011 Aug 4.