PMID- 21821854 OWN - NLM STAT- MEDLINE DCOM- 20120702 LR - 20111117 IS - 1532-2092 (Electronic) IS - 1099-5129 (Linking) VI - 13 IP - 12 DP - 2011 Dec TI - Gender disparities in anxiety and quality of life in patients with an implantable cardioverter-defibrillator. PG - 1723-30 LID - 10.1093/europace/eur252 [doi] AB - AIMS: A paucity of studies in implantable cardioverter-defibrillator (ICD) patients has examined gender disparities in patient-reported outcomes, such as anxiety and quality of life (QoL). We investigated (i) gender disparities in anxiety and QoL and (ii) the magnitude of the effect of gender vs. New York Heart Association (NYHA) functional class (III/IV), ICD shock, and Type D personality on these outcomes. METHODS AND RESULTS: Implantable cardioverter-defibrillator patients (n = 718; 81% men) completed the State-Trait Anxiety Inventory (STAI) and the Short-Form Health Survey 36 (SF-36) at baseline and 12 months post-implantation. The magnitude of the effect was indicated using Cohen's effect size index. Multivariate analysis of covariance for repeated measures showed no differences between men and women on mean scores of anxiety (F((1,696)) = 2.67, P = 0.10). Differences in QoL were observed for only two of the eight subscales of the SF-36, with women reporting poorer physical functioning (F((1,696)) = 7.14, P = 0.008) and vitality (F((1,696)) = 4.88, P = 0.028) than men. With respect to anxiety, effect sizes at baseline and 12 months for gender, NYHA class, and ICD shocks were small. A large effect size for Type D personality was found at both time points. For QoL, at baseline and 12 months, the effect sizes for gender were small, while the influence of NYHA class and Type D personality was moderate to large. CONCLUSIONS: Men and women did not differ on mean anxiety or QoL scores, except for women reporting poorer QoL on two domains. The relative influence of gender on anxiety and QoL was less than that of NYHA functional class and Type D personality. FAU - Habibovic, Mirela AU - Habibovic M AD - CoRPS-Department of Medical Psychology and Neuropsychology, Tilburg University, Tilburg, The Netherlands. FAU - van den Broek, Krista C AU - van den Broek KC FAU - Theuns, Dominic A M J AU - Theuns DA FAU - Jordaens, Luc AU - Jordaens L FAU - Alings, Marco AU - Alings M FAU - van der Voort, Pepijn H AU - van der Voort PH FAU - Pedersen, Susanne S AU - Pedersen SS LA - eng PT - Comparative Study PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't DEP - 20110806 PL - England TA - Europace JT - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JID - 100883649 SB - IM MH - Aged MH - Anxiety/epidemiology/*psychology MH - Arrhythmias, Cardiac/physiopathology/*therapy MH - Death, Sudden, Cardiac/*prevention & control MH - *Defibrillators, Implantable MH - Female MH - Follow-Up Studies MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Personality/physiology MH - Quality of Life/*psychology MH - Retrospective Studies MH - Severity of Illness Index MH - *Sex Characteristics MH - Treatment Outcome EDAT- 2011/08/09 06:00 MHDA- 2012/07/03 06:00 CRDT- 2011/08/09 06:00 PHST- 2011/08/09 06:00 [entrez] PHST- 2011/08/09 06:00 [pubmed] PHST- 2012/07/03 06:00 [medline] AID - eur252 [pii] AID - 10.1093/europace/eur252 [doi] PST - ppublish SO - Europace. 2011 Dec;13(12):1723-30. doi: 10.1093/europace/eur252. Epub 2011 Aug 6.