PMID- 21832305 OWN - NLM STAT- MEDLINE DCOM- 20120222 LR - 20191112 IS - 1543-2742 (Electronic) IS - 1526-484X (Linking) VI - 21 IP - 5 DP - 2011 Oct TI - The effect of adding caffeine to postexercise carbohydrate feeding on subsequent high-intensity interval-running capacity compared with carbohydrate alone. PG - 410-6 AB - The aim of this study was to test the hypothesis that adding caffeine to postexercise carbohydrate (CHO) feedings improves subsequent high-intensity interval-running capacity compared with CHO alone. In a repeated-measures design, 6 men performed a glycogen-depleting exercise protocol until volitional exhaustion in the morning. Immediately after and at 1, 2, and 3 hr postexercise, participants consumed 1.2 g/kg body mass CHO of a 15% CHO solution, a similar CHO solution but with addition of 8 mg/kg body mass of caffeine (CHO+CAFF), or an equivalent volume of flavored water only (WAT). After the 4-hr recovery period, participants performed the Loughborough Intermittent Shuttle Test (LIST) to volitional exhaustion as a measure of high-intensity interval-running capacity. Average blood glucose values during the 4-hr recovery period were higher in the CHO conditions (p < .005) than in the WAT trial (4.6 +/- 0.3 mmol/L), although there was no difference (p = .46) between CHO (6.2 +/- 0.8 mmol/L) and CHO+CAFF (6.7 +/- 1.0 mmol/L). Exercise capacity during the LIST was significantly longer in the CHO+CAFF trial (48 +/- 15 min) than in the CHO (32 +/- 15 min, p = .04) and WAT conditions (19 +/- 6 min, p = .001). All 6 participants improved performance in CHO+CAFF compared with CHO (95% CI for mean difference = 1-32 min). The study provides novel data by demonstrating that adding caffeine to postexercise CHO feeding improves subsequent high-intensity interval-running capacity, a finding that may be related to higher rates of postexercise muscle glycogen resynthesis previously observed under similar feeding conditions. FAU - Taylor, Conor AU - Taylor C AD - Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK. FAU - Higham, Daniel AU - Higham D FAU - Close, Graeme L AU - Close GL FAU - Morton, James P AU - Morton JP LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20110810 PL - United States TA - Int J Sport Nutr Exerc Metab JT - International journal of sport nutrition and exercise metabolism JID - 100939812 RN - 0 (Blood Glucose) RN - 0 (Central Nervous System Stimulants) RN - 0 (Dietary Carbohydrates) RN - 3G6A5W338E (Caffeine) RN - 9005-79-2 (Glycogen) SB - IM MH - Adult MH - Athletic Performance/physiology MH - Blood Glucose/*metabolism MH - Caffeine/*pharmacology MH - Central Nervous System Stimulants/*pharmacology MH - Dietary Carbohydrates/*pharmacology MH - Double-Blind Method MH - Glycogen/metabolism MH - Humans MH - Male MH - Physical Endurance/*physiology MH - Physical Exertion/*physiology MH - Physical Fitness/physiology MH - Rest/physiology MH - Running/*physiology MH - Young Adult EDAT- 2011/08/13 06:00 MHDA- 2012/02/23 06:00 CRDT- 2011/08/12 06:00 PHST- 2011/08/12 06:00 [entrez] PHST- 2011/08/13 06:00 [pubmed] PHST- 2012/02/23 06:00 [medline] AID - 2011_0028 [pii] AID - 10.1123/ijsnem.21.5.410 [doi] PST - ppublish SO - Int J Sport Nutr Exerc Metab. 2011 Oct;21(5):410-6. doi: 10.1123/ijsnem.21.5.410. Epub 2011 Aug 10.