PMID- 21838901 OWN - NLM STAT- MEDLINE DCOM- 20111223 LR - 20240117 IS - 1532-429X (Electronic) IS - 1097-6647 (Print) IS - 1097-6647 (Linking) VI - 13 IP - 1 DP - 2011 Aug 12 TI - Cardiovascular magnetic resonance in wet beriberi. PG - 41 LID - 10.1186/1532-429X-13-41 [doi] AB - The clinical presentation of beriberi can be quite varied. In the extreme form, profound cardiovascular involvement leads to circulatory collapse and death. This case report is of a 72 year-old male who was admitted to the Neurology inpatient ward with progressive bilateral lower extremity weakness and parasthesia. He subsequently developed pulmonary edema and high output cardiac failure requiring intubation and blood pressure support. With the constellation of peripheral neuropathy, encephalopathy, ophthalmoplegia, unexplained heart failure, and lactic acidosis, thiamine deficiency was suspected. He was empirically initiated on thiamine replacement therapy and his thiamine level pre-therapy was found to be 23 nmol/L (Normal: 80-150 nmol/L), consistent with the diagnosis of beriberi. Cardiovascular magnetic resonance (CMR) showed severe left ventricular systolic dysfunction, markedly increased myocardial T2, and minimal late gadolinium enhancement (LGE). After 5 days of daily 100 mg IV thiamine and supportive care, the hypotension resolved and the patient was extubated and was released from the hospital 3 weeks later. Our case shows via CMR profound myocardial edema associated with wet beriberi. FAU - Essa, Essa AU - Essa E AD - Division of Cardiovascular Medicine, The Ohio State University, Davis Heart & Lung Research Institute, Suite 200, 473 W, 12th Avenue, Columbus, Ohio 43210-1252, USA. FAU - Velez, Michael R AU - Velez MR FAU - Smith, Sakima AU - Smith S FAU - Giri, Shivraman AU - Giri S FAU - Raman, Subha V AU - Raman SV FAU - Gumina, Richard J AU - Gumina RJ LA - eng PT - Case Reports PT - Journal Article DEP - 20110812 PL - England TA - J Cardiovasc Magn Reson JT - Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance JID - 9815616 RN - X66NSO3N35 (Thiamine) SB - IM MH - Aged MH - Beriberi/complications/*diagnosis/therapy MH - Edema, Cardiac/*diagnosis/etiology/therapy MH - Heart Failure/*diagnosis/etiology/therapy MH - Humans MH - *Magnetic Resonance Imaging, Cine MH - Male MH - Myocardium/*pathology MH - Predictive Value of Tests MH - Pulmonary Edema/diagnosis/etiology/therapy MH - Severity of Illness Index MH - Thiamine/administration & dosage MH - Treatment Outcome MH - Ventricular Dysfunction, Left/*diagnosis/etiology/therapy PMC - PMC3175447 EDAT- 2011/08/16 06:00 MHDA- 2011/12/24 06:00 PMCR- 2011/08/12 CRDT- 2011/08/16 06:00 PHST- 2011/04/26 00:00 [received] PHST- 2011/08/12 00:00 [accepted] PHST- 2011/08/16 06:00 [entrez] PHST- 2011/08/16 06:00 [pubmed] PHST- 2011/12/24 06:00 [medline] PHST- 2011/08/12 00:00 [pmc-release] AID - S1097-6647(23)01396-0 [pii] AID - 1532-429X-13-41 [pii] AID - 10.1186/1532-429X-13-41 [doi] PST - epublish SO - J Cardiovasc Magn Reson. 2011 Aug 12;13(1):41. doi: 10.1186/1532-429X-13-41.