PMID- 21851000 OWN - NLM STAT- MEDLINE DCOM- 20110914 LR - 20190816 IS - 0869-2084 (Print) IS - 0869-2084 (Linking) IP - 6 DP - 2011 Jun TI - [Role of vascular endothelial growth factor and monocyte chemoattractant protein-1 in the development of endothelial dysfunction in types 1 and 2 diabetes mellitus complicated by diabetic retinopathy]. PG - 8-10 AB - The paper presents the results of a study of the serum levels of monocyte chemoattractant protein-1 (MCP-1) and vascular endothelial growth factor (VEGF) in 120 patients with types 1 and 2 diabetes mellitus complicated by diabetic retinopathy. All the patients with diabetes have been ascertained to show a rise in the levels of MCP-1 and VEGF. Calculation of VEGF/MCP-1 ratio is proposed to evaluate vascular bed lesion in diabetic patients. FAU - Nikitina, V V AU - Nikitina VV FAU - Zakharova, N B AU - Zakharova NB FAU - Kamenskikh, T G AU - Kamenskikh TG LA - rus PT - English Abstract PT - Journal Article PL - Russia (Federation) TA - Klin Lab Diagn JT - Klinicheskaia laboratornaia diagnostika JID - 9432021 RN - 0 (CCL2 protein, human) RN - 0 (Chemokine CCL2) RN - 0 (Vascular Endothelial Growth Factor A) SB - IM MH - Adolescent MH - Adult MH - Chemokine CCL2/*blood MH - Diabetes Mellitus, Type 1/*complications MH - Diabetes Mellitus, Type 2/*complications MH - Diabetic Retinopathy/*blood/etiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Vascular Endothelial Growth Factor A/*blood EDAT- 2011/08/20 06:00 MHDA- 2011/09/15 06:00 CRDT- 2011/08/20 06:00 PHST- 2011/08/20 06:00 [entrez] PHST- 2011/08/20 06:00 [pubmed] PHST- 2011/09/15 06:00 [medline] PST - ppublish SO - Klin Lab Diagn. 2011 Jun;(6):8-10.