PMID- 21852770
OWN - NLM
STAT- MEDLINE
DCOM- 20121015
LR  - 20161125
IS  - 1476-5543 (Electronic)
IS  - 0743-8346 (Linking)
VI  - 32
IP  - 3
DP  - 2012 Mar
TI  - Risk factors for maternal outcome in pregnancy complicated with dilated 
      cardiomyopathy.
PG  - 170-5
LID - 10.1038/jp.2011.81 [doi]
AB  - OBJECTIVE: The goal of the study was to determine risk factors for maternal 
      cardiac failure in pregnancy complicated with dilated cardiomyopathy (DCM). STUDY 
      DESIGN: The subjects were 29 patients diagnosed with DCM before conception or 
      during the first 7 months of pregnancy. DCM was defined as left ventricle 
      end-diastolic dimension (LVDd)>/=48 mm and/or fractional shortening (%FS)</=30% on 
      echocardiography. Patients were followed until at least 1 year after delivery and 
      were categorized into a poor prognosis group (n=6; death or end stage heart 
      failure of New York Heart Association (NYHA) class III and IV) and a good 
      prognosis group (n=23; all other cases). RESULT: DCM was initially diagnosed 
      during pregnancy in 6/6 and 8/23 patients in the poor and good prognosis groups, 
      respectively (P<0.005). The %FS of the first test during pregnancy was 17.5+/-6.2 
      and 27.4+/-9.3% in the respective groups (P<0.005). In eight abortion cases with 
      %FS 15.2+/-3.1%, %FS, cardiac function and NYHA class were maintained until 20 
      months after abortion. There was no relationship between LVDd and maternal 
      outcome. CONCLUSION: Onset during pregnancy and decreased %FS are risk factors 
      for a poor maternal outcome in patients with DCM. Abortion prevents further 
      deterioration of cardiac function in patients with a very low %FS.
FAU - Katsuragi, S
AU  - Katsuragi S
AD  - Department of Perinatology and Gynecology, National Cerebral and Cardiovascular 
      Center, Osaka, Japan. skatsura12@yahoo.co.jp
FAU - Omoto, A
AU  - Omoto A
FAU - Kamiya, C
AU  - Kamiya C
FAU - Ueda, K
AU  - Ueda K
FAU - Sasaki, Y
AU  - Sasaki Y
FAU - Yamanaka, K
AU  - Yamanaka K
FAU - Neki, R
AU  - Neki R
FAU - Yoshimatsu, J
AU  - Yoshimatsu J
FAU - Niwa, K
AU  - Niwa K
FAU - Ikeda, T
AU  - Ikeda T
LA  - eng
PT  - Journal Article
DEP - 20110818
PL  - United States
TA  - J Perinatol
JT  - Journal of perinatology : official journal of the California Perinatal 
      Association
JID - 8501884
SB  - IM
CIN - J Perinatol. 2012 Mar;32(3):161-2. PMID: 22370895
MH  - Adult
MH  - Cardiomyopathy, Dilated/*complications/diagnostic imaging
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/*etiology
MH  - Heart Ventricles/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Pregnancy
MH  - *Pregnancy Complications, Cardiovascular/diagnostic imaging
MH  - Prognosis
MH  - Risk Factors
MH  - Ventricular Dysfunction, Left/diagnostic imaging/*etiology
MH  - Young Adult
EDAT- 2011/08/20 06:00
MHDA- 2012/10/16 06:00
CRDT- 2011/08/20 06:00
PHST- 2011/08/20 06:00 [entrez]
PHST- 2011/08/20 06:00 [pubmed]
PHST- 2012/10/16 06:00 [medline]
AID - jp201181 [pii]
AID - 10.1038/jp.2011.81 [doi]
PST - ppublish
SO  - J Perinatol. 2012 Mar;32(3):170-5. doi: 10.1038/jp.2011.81. Epub 2011 Aug 18.