PMID- 21860905 OWN - NLM STAT- MEDLINE DCOM- 20120203 LR - 20190907 IS - 1678-9849 (Electronic) IS - 0037-8682 (Linking) VI - 44 IP - 4 DP - 2011 Jul-Aug TI - Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature. PG - 522-5 LID - S0037-86822011000400026 [pii] AB - The reactivation of human herpesvirus 6 (HHV-6) in patients with AIDS can result in an acute and severe diffuse meningoencephalitis. We describe the epidemiological, clinical and outcome findings of five patients with diagnosis of HIV/AIDS and central nervous system involvement (CNS) due to HHV-6. Fever was present in all the patients. Meningeal compromise, seizures and encephalitis were present in some of the patients. Polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) specimens was positive for HHV-6 in all the patients. HHV-6 should be included among opportunistic and emerging pathogens that involve the CNS in patients with AIDS. FAU - Corti, Marcelo AU - Corti M AD - Hospital de Enfermidades Infecciosas Francisco Javier Muniz, Buenos Aires, Argentina. marcelocorti@fibertel.com.ar FAU - Villafane, Maria Florencia AU - Villafane MF FAU - Trione, Norberto AU - Trione N FAU - Mamanna, Lilia AU - Mamanna L FAU - Bouzas, Belen AU - Bouzas B LA - eng PT - Case Reports PT - Journal Article PT - Review PL - Brazil TA - Rev Soc Bras Med Trop JT - Revista da Sociedade Brasileira de Medicina Tropical JID - 7507456 SB - IM MH - AIDS-Related Opportunistic Infections/cerebrospinal fluid/*virology MH - Adult MH - Communicable Diseases, Emerging/cerebrospinal fluid/*virology MH - Female MH - Herpesviridae Infections/cerebrospinal fluid/*virology MH - Herpesvirus 6, Human/*genetics MH - Humans MH - Male MH - Meningoencephalitis/cerebrospinal fluid/*virology MH - Middle Aged MH - Polymerase Chain Reaction EDAT- 2011/08/24 06:00 MHDA- 2012/02/04 06:00 CRDT- 2011/08/24 06:00 PHST- 2010/03/12 00:00 [received] PHST- 2011/01/25 00:00 [accepted] PHST- 2011/08/24 06:00 [entrez] PHST- 2011/08/24 06:00 [pubmed] PHST- 2012/02/04 06:00 [medline] AID - S0037-86822011000400026 [pii] AID - 10.1590/s0037-86822011000400026 [doi] PST - ppublish SO - Rev Soc Bras Med Trop. 2011 Jul-Aug;44(4):522-5. doi: 10.1590/s0037-86822011000400026.