PMID- 21868718 OWN - NLM STAT- MEDLINE DCOM- 20120727 LR - 20120302 IS - 1941-2444 (Electronic) IS - 0148-6071 (Linking) VI - 36 IP - 2 DP - 2012 Mar TI - Percutaneous endoscopic gastrostomy complication rates and compliance with the American Society for Gastrointestinal Endoscopy guidelines for the management of antithrombotic therapy. PG - 226-30 LID - 10.1177/0148607111413897 [doi] AB - BACKGROUND: The American Society for Gastrointestinal Endoscopy (ASGE) has published recommendations in regards to anticoagulant (AC) and antiplatelet (AP) therapy management during endoscopic procedures. So far, no study has assessed either ASGE recommendation compliance during percutaneous endoscopic gastrostomy (PEG) placement or procedure-associated complication rates as related to the observance of these recommendations. The aims of this study were to compare the incidence and type of complications during PEG placement in patients receiving or not receiving AC and/or AP therapy and to determine the compliance with ASGE's AC and AP management guidelines. METHODS: Medical files of patients who underwent PEG placement from January 2004 to December 2008 were reviewed. Clinical and procedure-related data were recorded. Patients were separated into 1 of 2 groups: patients under AP and/or AC therapy prior to PEG placement (n = 51) and a control group of patients (n = 40) not receiving any AP and/or AC treatment at least 6 months prior to the procedure. RESULTS: A total of 91 patients (51 cases) were included. Groups were comparable in demographics and clinical characteristics. No differences in the frequency and type of complications were found between groups. ASGE's recommendations were not followed in any of these patients. CONCLUSIONS: Overall PEG placement complication rate was 13.7%. AP therapy may be safely discontinued closer to the time of endoscopic procedure than the time currently recommended by the ASGE guidelines. FAU - Lozoya-Gonzalez, Diego AU - Lozoya-Gonzalez D AD - Advanced Endoscopy Unit, ABC Medical Center, Mexico DF, Mexico. FAU - Pelaez-Luna, Mario AU - Pelaez-Luna M FAU - Farca-Belsaguy, Alberto AU - Farca-Belsaguy A FAU - Salceda-Otero, Juan C AU - Salceda-Otero JC FAU - Vazquez-Ballesteros, Edgar AU - Vazquez-Ballesteros E LA - eng PT - Comparative Study PT - Journal Article DEP - 20110825 PL - United States TA - JPEN J Parenter Enteral Nutr JT - JPEN. Journal of parenteral and enteral nutrition JID - 7804134 RN - 0 (Anticoagulants) RN - 0 (Platelet Aggregation Inhibitors) SB - IM MH - Aged MH - Aged, 80 and over MH - Anticoagulants/*therapeutic use MH - Disease Management MH - Enteral Nutrition/methods MH - Female MH - Gastroscopy/*adverse effects/methods MH - Gastrostomy/*adverse effects/methods MH - *Guideline Adherence MH - Humans MH - Incidence MH - Intubation, Gastrointestinal/*adverse effects MH - Male MH - Middle Aged MH - Platelet Aggregation Inhibitors/*therapeutic use MH - Postoperative Complications/*epidemiology MH - Practice Guidelines as Topic MH - Societies, Medical MH - Thrombosis/prevention & control EDAT- 2011/08/27 06:00 MHDA- 2012/07/28 06:00 CRDT- 2011/08/27 06:00 PHST- 2011/08/27 06:00 [entrez] PHST- 2011/08/27 06:00 [pubmed] PHST- 2012/07/28 06:00 [medline] AID - 0148607111413897 [pii] AID - 10.1177/0148607111413897 [doi] PST - ppublish SO - JPEN J Parenter Enteral Nutr. 2012 Mar;36(2):226-30. doi: 10.1177/0148607111413897. Epub 2011 Aug 25.