PMID- 21871664
OWN - NLM
STAT- MEDLINE
DCOM- 20120224
LR  - 20181201
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 74
IP  - 8
DP  - 2011 Nov
TI  - Early life developmental effects of marine persistent organic pollutants on the 
      sea urchin Psammechinus miliaris.
PG  - 2182-92
LID - 10.1016/j.ecoenv.2011.07.037 [doi]
AB  - A new 16-day echinoid early life stage (ELS) bioassay was developed to allow for 
      prolonged observation of possible adverse effects during embryogenesis and larval 
      development of the sea urchin Psammechinus miliaris. Subsequently, the newly 
      developed bioassay was applied to study the effects of key marine persistent 
      organic pollutants (POPs). Mortality, morphological abnormalities and larval 
      development stages were quantified at specific time points during the 16-day 
      experimental period. In contrast to amphibians and fish, P. miliaris early life 
      development was not sensitive to dioxin-like toxicity in the prolonged early life 
      stage test. Triclosan (TCS) levels higher than 500 nM were acutely toxic during 
      embryo development. Morphological abnormalities were induced at concentrations 
      higher than 50 nM hexabromocyclododecane (HBCD) and 1000 nM tetrabromobisphenol A 
      (TBBPA). Larval development was delayed above 25 nM HBCD and 500 nM TBBPA. 
      Heptadecafluorooctane sulfonic acid (PFOS) exposure slightly accelerated larval 
      development at 9 days post-fertilization (dpf). However, the accelerated 
      development was no longer observed at the end of the test period (16 dpf). The 
      newly developed 16-day echinoid ELS bioassay proved to be sensitive to toxic 
      effects of POPs that can be monitored for individual echinoid larvae. The most 
      sensitive and dose related endpoint was the number of developmental penalty 
      points. By manipulation of the housing conditions, the reproductive season could 
      be extended from 3 to 9 months per year and the ELS experiments could be 
      performed in artificial sea water as well.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Anselmo, Henrique M R
AU  - Anselmo HM
AD  - Wageningen IMARES, Institute for Marine Resources & Ecosystem Studies, P.O. Box 
      57, 1780 AB Den Helder, The Netherlands. henrique.anselmo@wur.nl
FAU - Koerting, Lina
AU  - Koerting L
FAU - Devito, Sarah
AU  - Devito S
FAU - van den Berg, Johannes H J
AU  - van den Berg JH
FAU - Dubbeldam, Marco
AU  - Dubbeldam M
FAU - Kwadijk, Christiaan
AU  - Kwadijk C
FAU - Murk, Albertinka J
AU  - Murk AJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110825
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Hydrocarbons, Brominated)
RN  - 0 (Organic Chemicals)
RN  - 0 (Polybrominated Biphenyls)
RN  - 0 (Water Pollutants, Chemical)
RN  - 4NM5039Y5X (Triclosan)
RN  - 5I9835JO3M (hexabromocyclododecane)
RN  - FQI02RFC3A (tetrabromobisphenol A)
SB  - IM
EIN - Ecotoxicol Environ Saf. 2012 Jun;80:401
MH  - Animals
MH  - Embryonic Development/drug effects
MH  - Fertilization/drug effects
MH  - Hydrocarbons, Brominated/toxicity
MH  - Larva/drug effects/growth & development
MH  - Organic Chemicals/*toxicity
MH  - Polybrominated Biphenyls/toxicity
MH  - Sea Urchins/*drug effects/growth & development
MH  - Seawater/chemistry
MH  - Triclosan/toxicity
MH  - Water Pollutants, Chemical/*toxicity
EDAT- 2011/08/30 06:00
MHDA- 2012/03/01 06:00
CRDT- 2011/08/30 06:00
PHST- 2011/02/28 00:00 [received]
PHST- 2011/07/27 00:00 [revised]
PHST- 2011/07/30 00:00 [accepted]
PHST- 2011/08/30 06:00 [entrez]
PHST- 2011/08/30 06:00 [pubmed]
PHST- 2012/03/01 06:00 [medline]
AID - S0147-6513(11)00242-9 [pii]
AID - 10.1016/j.ecoenv.2011.07.037 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2011 Nov;74(8):2182-92. doi: 
      10.1016/j.ecoenv.2011.07.037. Epub 2011 Aug 25.