PMID- 21872756
OWN - NLM
STAT- MEDLINE
DCOM- 20120315
LR  - 20211020
IS  - 1558-4224 (Electronic)
IS  - 0749-0739 (Print)
IS  - 0749-0739 (Linking)
VI  - 27
IP  - 2
DP  - 2011 Aug
TI  - Embryonic stem cells and iPS cells: sources and characteristics.
PG  - 233-42
LID - 10.1016/j.cveq.2011.04.003 [doi]
AB  - The field of regenerative medicine research is rapidly expanding. One area of 
      interest to equine researchers is the possibility of isolating or generating 
      pluripotent cells, capable of producing differentiated cell types derived from 
      all 3 primary germ layers. Reports of equine embryonic stem-like (ES) cell 
      isolation can be found in the literature. Other groups are working to produce 
      equine-induced pluripotent stem (iPS) cells. This article summarizes the 
      essential features needed to characterize a cell type as pluripotent, specific 
      challenges in using the horse as a model organism for pluripotent cell 
      generation, and current and upcoming clinical trials using ES/iPS cells.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Hackett, Catherine H
AU  - Hackett CH
AD  - Department of Clinical Sciences, Box 32, Veterinary Medical Center, College of 
      Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
FAU - Fortier, Lisa A
AU  - Fortier LA
LA  - eng
GR  - F32 AR056187/AR/NIAMS NIH HHS/United States
PT  - Journal Article
DEP - 20110616
PL  - United States
TA  - Vet Clin North Am Equine Pract
JT  - The Veterinary clinics of North America. Equine practice
JID - 8511904
SB  - IM
MH  - Animals
MH  - Cell Culture Techniques
MH  - Clinical Trials as Topic
MH  - Embryonic Stem Cells/*cytology/*physiology/transplantation
MH  - Horses
MH  - Humans
MH  - Induced Pluripotent Stem Cells/*cytology/*physiology/transplantation
MH  - Mice
MH  - Stem Cell Research
PMC - PMC3479634
MID - NIHMS305936
EDAT- 2011/08/30 06:00
MHDA- 2012/03/16 06:00
PMCR- 2012/10/24
CRDT- 2011/08/30 06:00
PHST- 2011/08/30 06:00 [entrez]
PHST- 2011/08/30 06:00 [pubmed]
PHST- 2012/03/16 06:00 [medline]
PHST- 2012/10/24 00:00 [pmc-release]
AID - S0749-0739(11)00023-X [pii]
AID - 10.1016/j.cveq.2011.04.003 [doi]
PST - ppublish
SO  - Vet Clin North Am Equine Pract. 2011 Aug;27(2):233-42. doi: 
      10.1016/j.cveq.2011.04.003. Epub 2011 Jun 16.