PMID- 21878207
OWN - NLM
STAT- MEDLINE
DCOM- 20111027
LR  - 20240507
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Print)
IS  - 0003-9993 (Linking)
VI  - 92
IP  - 9
DP  - 2011 Sep
TI  - Combined aerobic and resistance exercise program improves task performance in 
      patients with heart failure.
PG  - 1371-81
LID - 10.1016/j.apmr.2011.02.022 [doi]
AB  - OBJECTIVES: To assess the effects of a home-based aerobic and resistance training 
      program on the physical function of adults with New York Heart Association (NYHA) 
      class II and III patients and systolic heart failure (HF). DESIGN: Randomized 
      controlled trial. SETTING: Home based. PARTICIPANTS: Stable patients (N=24; mean 
      age, 60 +/- 10 y; left ventricular ejection fraction, 25% +/- 9%; 50% white; 50% 
      women) with New York Heart Association (NYHA) classes II and III (NYHA class III, 
      58%) systolic heart failure (HF). INTERVENTION: A 12-week progressive home-based 
      program of moderate-intensity aerobic and resistance exercise. Attention control 
      wait list participants performed light stretching and flexibility exercises. MAIN 
      OUTCOME MEASURES: A 10-item performance-based physical function measure, the 
      Continuous Scale Physical Functional Performance test (CS-PFP10), was the major 
      outcome variable and included specific physical activities measured in time to 
      complete a task, weight carried during a task, and distance walked. Other 
      measures included muscle strength, HRQOL (Minnesota Living With Heart Failure 
      Questionnaire, Epworth Sleepiness Scale), functional capacity (Duke Activity 
      Status Index), and disease severity (brain natriuretic peptide) levels. RESULTS: 
      After the exercise intervention, 9 of 10 specific task activities were performed 
      more rapidly, with increased weight carried by exercise participants compared 
      with the attention control wait list group. Exercise participants also showed 
      significant improvements in CS-PFP10 total score (P<.025), upper and lower muscle 
      strength, and HRQOL (P<.001) compared with the attention control wait list group. 
      Adherence rates were 83% and 99% for the aerobic and resistance training, 
      respectively. CONCLUSIONS: Patients with stable HF who participate in a 
      moderate-intensity combined aerobic and resistance exercise program may improve 
      performance of routine physical activities of daily living by using a home-based 
      exercise approach. Performance-based measures such as the CS-PFP10 may provide 
      additional insights into physical function in patients with HF that more commonly 
      used exercise tests may not identify. Early detection of subtle changes that may 
      signal declining physical function that are amenable to intervention potentially 
      may slow further loss of function in this patient population.
CI  - Copyright (c) 2011 American Congress of Rehabilitation Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Gary, Rebecca A
AU  - Gary RA
AD  - Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA. 
      ragary@emory.edu
FAU - Cress, M Elaine
AU  - Cress ME
FAU - Higgins, Melinda K
AU  - Higgins MK
FAU - Smith, Andrew L
AU  - Smith AL
FAU - Dunbar, Sandra B
AU  - Dunbar SB
LA  - eng
GR  - TL1 RR025010/RR/NCRR NIH HHS/United States
GR  - TL1 TR000456/TR/NCATS NIH HHS/United States
GR  - UL1 RR025008/RR/NCRR NIH HHS/United States
GR  - UL1 TR000454/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Activities of Daily Living
MH  - Adult
MH  - Aged
MH  - Exercise/*physiology
MH  - Exercise Therapy/*methods
MH  - Female
MH  - Hand Strength
MH  - Heart Failure/physiopathology/psychology/*rehabilitation
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/biosynthesis
MH  - Quality of Life
MH  - Resistance Training/methods
MH  - Walking
PMC - PMC4143394
MID - NIHMS614733
COIS- No commercial party having a direct financial interest in the results of the 
      research supporting this article has or will confer a benefit on the authors or 
      on any organization with which the authors are associated.
EDAT- 2011/09/01 06:00
MHDA- 2011/10/28 06:00
PMCR- 2014/08/25
CRDT- 2011/09/01 06:00
PHST- 2011/02/05 00:00 [received]
PHST- 2011/02/28 00:00 [accepted]
PHST- 2011/09/01 06:00 [entrez]
PHST- 2011/09/01 06:00 [pubmed]
PHST- 2011/10/28 06:00 [medline]
PHST- 2014/08/25 00:00 [pmc-release]
AID - S0003-9993(11)00198-5 [pii]
AID - 10.1016/j.apmr.2011.02.022 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2011 Sep;92(9):1371-81. doi: 10.1016/j.apmr.2011.02.022.