PMID- 21879000
OWN - NLM
STAT- MEDLINE
DCOM- 20120320
LR  - 20211203
IS  - 1476-5543 (Electronic)
IS  - 0743-8346 (Linking)
VI  - 31
IP  - 9
DP  - 2011 Sep
TI  - Evaluating neonatal hyperbilirubinemia in late preterm Hispanic twins led to the 
      diagnosis of hereditary spherocytosis in them, and in their sibling and in their 
      mother.
PG  - 625-7
LID - 10.1038/jp.2010.212 [doi]
AB  - We identified four cases of hereditary spherocytosis (HS) in one Utah family, 
      originally from Southwestern Mexico. The index cases were twin girls born at 35 
      weeks gestation, in whom the combination of hyperbilirubinemia, reticulocytosis 
      and elevated mean corpuscular hemoglobin concentration (MCHC) led to studies that 
      confirmed the diagnosis of HS. Scleral icterus in their 4-year-old sibling and in 
      their mother led to the diagnosis of HS in them as well. Although much less 
      commonly reported in Hispanic neonates than in those of Northern European 
      ancestry, HS does occur among Hispanic neonates and can contribute to significant 
      neonatal hyperbilirubinemia. These cases are consistent with our earlier report, 
      which identified an MCHC cutoff of >36 as suggestive of further evaluation for 
      HS.
FAU - Sheffield, M J
AU  - Sheffield MJ
AD  - Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT 
      84403, USA. Mark.sheffield@imail.org
FAU - Christensen, R D
AU  - Christensen RD
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Twin Study
PL  - United States
TA  - J Perinatol
JT  - Journal of perinatology : official journal of the California Perinatal 
      Association
JID - 8501884
SB  - IM
MH  - Adult
MH  - Diseases in Twins
MH  - Female
MH  - Hispanic or Latino
MH  - Humans
MH  - Hyperbilirubinemia, Neonatal/*blood/*diagnosis
MH  - Infant, Newborn
MH  - Neonatal Screening
MH  - Premature Birth
MH  - Spherocytosis, Hereditary/*blood/*diagnosis
EDAT- 2011/09/01 06:00
MHDA- 2012/03/21 06:00
CRDT- 2011/09/01 06:00
PHST- 2011/09/01 06:00 [entrez]
PHST- 2011/09/01 06:00 [pubmed]
PHST- 2012/03/21 06:00 [medline]
AID - jp2010212 [pii]
AID - 10.1038/jp.2010.212 [doi]
PST - ppublish
SO  - J Perinatol. 2011 Sep;31(9):625-7. doi: 10.1038/jp.2010.212.