PMID- 21880510 OWN - NLM STAT- MEDLINE DCOM- 20121123 LR - 20151119 IS - 1532-8422 (Electronic) IS - 1053-0770 (Linking) VI - 26 IP - 2 DP - 2012 Apr TI - A comparison of endotracheal bioimpedance cardiography and transpulmonary thermodilution in cardiac surgery patients. PG - 217-22 LID - 10.1053/j.jvca.2011.06.023 [doi] AB - OBJECTIVES: The authors hypothesized that bioimpedance cardiography measured by the Endotracheal Cardiac Output Monitor (ECOM; ConMed, Utica, NY) is a convenient and reliable method for both cardiac index (CI) assessment and prediction in fluid responsiveness. DESIGN: A prospective observational study. SETTING: A teaching university hospital. PARTICIPANTS: Twenty-five adult patients. INTERVENTIONS: Admission to the intensive care unit after conventional cardiac surgery and investigation before and after a fluid challenge. MEASUREMENTS AND MAIN RESULTS: Simultaneous comparative CI data points were collected from transpulmonary thermodilution (TD) and ECOM. Correlations were determined by linear regression. Bland-Altman analysis was used to compare the bias, precision, and limits of agreement. The percentage error was calculated. Pulse-pressure variations (PPVs) and stroke-volume variations (SVVs) before fluid challenge were collected to assess their discrimination in predicting fluid responsiveness. A weak but statistically significant relationship was found between CI(TD) and CI(ECOM) (r = 0.31, p = 0.03). Bias, precision, and limits of agreement between CI(TD) and CI(ECOM) were 0.08 L/min/m(2) (95% confidence interval, -0.11 to 0.27), 0.68 L/min/m(2), and -1.26 to 1.42 L/min/m(2), respectively. The percentage error was 51%. A nonsignificant positive relationship was found between percent changes in CI(TD) and CI(ECOM) after fluid challenge (r = 0.37, p = 0.06). Areas under the ROC curves for both PPV and SVV to predict fluid responsiveness were 0.86 (95% confidence interval, 0.67-1.06) and 0.89 (95% confidence interval, 0.74-1.04, respectively; p = 0.623). CONCLUSIONS: Continuous measurements of CI under dynamic conditions are consistent and easy to obtain with ECOM although not interchangeable with transpulmonary thermodilution. SVV given by ECOM is a dynamic parameter that predicts fluid responsiveness with good accuracy and discrimination. CI - Copyright A(c) 2012 Elsevier Inc. All rights reserved. FAU - Fellahi, Jean-Luc AU - Fellahi JL AD - Department of Anesthesiology and Critical Care Medicine, CHU de Caen, Caen, France. fellahi-jl@chu-caen.fr FAU - Fischer, Marc-Olivier AU - Fischer MO FAU - Rebet, Olivier AU - Rebet O FAU - Massetti, Massimo AU - Massetti M FAU - Gerard, Jean-Louis AU - Gerard JL FAU - Hanouz, Jean-Luc AU - Hanouz JL LA - eng PT - Comparative Study PT - Journal Article DEP - 20110831 PL - United States TA - J Cardiothorac Vasc Anesth JT - Journal of cardiothoracic and vascular anesthesia JID - 9110208 SB - IM MH - Aged MH - Cardiac Output/*physiology MH - Cardiac Surgical Procedures/*methods MH - Cardiography, Impedance/methods MH - Electric Impedance MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Thermodilution/methods EDAT- 2011/09/02 06:00 MHDA- 2012/12/10 06:00 CRDT- 2011/09/02 06:00 PHST- 2011/05/06 00:00 [received] PHST- 2011/09/02 06:00 [entrez] PHST- 2011/09/02 06:00 [pubmed] PHST- 2012/12/10 06:00 [medline] AID - S1053-0770(11)00469-1 [pii] AID - 10.1053/j.jvca.2011.06.023 [doi] PST - ppublish SO - J Cardiothorac Vasc Anesth. 2012 Apr;26(2):217-22. doi: 10.1053/j.jvca.2011.06.023. Epub 2011 Aug 31.