PMID- 21881305
OWN - NLM
STAT- MEDLINE
DCOM- 20120224
LR  - 20190724
IS  - 1347-5231 (Electronic)
IS  - 0031-6903 (Linking)
VI  - 131
IP  - 9
DP  - 2011
TI  - [Effect of environmental factor influencing the development of mouse cerebral 
      cortex].
PG  - 1317-21
AB  - The cerebral cortex is organized into six cell layers, each of which contains 
      neurons with similar morphology, functions, gene-expression profiles, and 
      projection patterns. These layer-specific neuronal phenotypes are sequentially 
      generated from common cortical progenitor cells in the ventricular zone of dorsal 
      telencephalon. Although recent investigations have clarified important roles of 
      intrinsic factors such as transcription factors and regulators of the cell cycle 
      for the maturation of cortical progenitors, growth factors and neurotrophic 
      factors environmentally supplied by the cerebral cortex are thought to regulate 
      proliferation and neural development and determine neuronal differentiation in 
      the cerebral cortex. In this review, I focus on the function of 
      neurotrophin-family neurotrophic factor, including nerve growth factor, 
      brain-derived neurotrophic factor (BDNF), neurotropin-3 (NT-3) and neurotrophin-4 
      in the formation of the neuronal layer of the cerebral cortex. Especially, BDNF 
      and NT-3 are expressed in the proliferating cortical progenitors and influence 
      the biological properties of cortical progenitors prior to neurogenesis and play 
      distinct roles in generation of cortical neuronal subtypes.
FAU - Fukumitsu, Hidefumi
AU  - Fukumitsu H
AD  - Laboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu 
      Pharmaceutical University, Gifu, Japan. hfukumi@gifu-pu.ac.jp
LA  - jpn
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Yakugaku Zasshi
JT  - Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
JID - 0413613
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Nerve Growth Factors)
RN  - 0 (neurotropin 3, mouse)
RN  - 9061-61-4 (Nerve Growth Factor)
RN  - P658DCA9XD (neurotrophin 4)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*physiology
MH  - Cell Differentiation/*genetics
MH  - *Cell Proliferation
MH  - Cerebral Cortex/*cytology/*growth & development
MH  - Mice
MH  - Nerve Growth Factor/*physiology
MH  - Nerve Growth Factors/*physiology
MH  - Neurogenesis/genetics
MH  - Neurons/*cytology
MH  - Stem Cells/*cytology
EDAT- 2011/09/02 06:00
MHDA- 2012/03/01 06:00
CRDT- 2011/09/02 06:00
PHST- 2011/09/02 06:00 [entrez]
PHST- 2011/09/02 06:00 [pubmed]
PHST- 2012/03/01 06:00 [medline]
AID - JST.JSTAGE/yakushi/131.1317 [pii]
AID - 10.1248/yakushi.131.1317 [doi]
PST - ppublish
SO  - Yakugaku Zasshi. 2011;131(9):1317-21. doi: 10.1248/yakushi.131.1317.