PMID- 21881716
OWN - NLM
STAT- MEDLINE
DCOM- 20111220
LR  - 20191210
VI  - 26
IP  - 1
DP  - 2011 Jan-Mar
TI  - Long term results of septal myectomy in the treatment of obstructive hypertrophic 
      cardiomyopathy.
PG  - 86-92
LID - S0102-76382011000100016 [pii]
AB  - OBJECTIVE: This study analyzed the clinical and echocardiographic late outcomes 
      of surgical septal myectomy in patients with obstructive hypertrophic 
      cardiomyopathy (OHCM). METHODS: We examined, retrospectively, 34 consecutive 
      adult patients (age 55.7+/-15.2 years) with OHCM operated on in our institution 
      from 1988 to 2008. Only four (11.8%) patients had family history of OHCM. Nine 
      (26.5%) patients were in New York Heart Association (NYHA) funcional class IV. 
      Thirty (88.2%) patients had solely OHCM, and four (11.8%) had OHCM associated 
      with coronary insufficiency. The surgical technique used in all patients was 
      septal myectomy performed through an aortotomy. RESULTS: In 26 (76.5%) patients 
      the mitral insufficiency due to systolic anterior motion, decreased after the 
      myectomy. Eight (23.5%) patients had mitral valve procedures. There was one 
      hospitalar death (2.9%). Two (5.9%) patients required permanent pacemaker for 
      complete heart block after the myectomy. The mean peak preoperative left 
      ventricular outflow tract (LVOT) obstruction gradient was 84.9+/-29.0 mmHg, and 
      decreased to 27.8+/-12.9 mmHg in the early postoperative and it was 19.2+/-11.2 mmHg 
      in the late postoperative period (49.0+/-33.0 months). The NYHA functional class 
      improved from 3.1+/-0.8 to 1.4+/-0.5 in the postoperative period. Survival free from 
      death was 87.9% and survival free from cardiovascular events was 77.7% with mean 
      follow-up 9.6+/-8.4 years. CONCLUSION: Surgical septal myectomy can be performed 
      safely, with excellent survival, improvement from symptoms and relief for LVOT 
      obstruction in patients with OHCM. The early benefits were remained at long term.
FAU - Lisboa, Luiz Augusto Ferreira
AU  - Lisboa LA
AD  - University of Sao Paulo School of Medicine (FMUSP). luiz.lisboa@incor.usp.br
FAU - Dallan, Luis Alberto Oliveira
AU  - Dallan LA
FAU - Pomerantzeff, Pablo Maria Alberto
AU  - Pomerantzeff PM
FAU - Oliveiras, Sergio Almeida de
AU  - Oliveiras SA
FAU - Jatene, Fabio Biscegli
AU  - Jatene FB
FAU - Stolf, Noedir Antonio Groppo
AU  - Stolf NA
LA  - eng
LA  - por
PT  - Evaluation Study
PT  - Journal Article
PL  - Brazil
TA  - Rev Bras Cir Cardiovasc
JT  - Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade 
      Brasileira de Cirurgia Cardiovascular
JID - 9104279
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiac Surgical Procedures/adverse effects/*methods/mortality
MH  - Cardiomyopathy, Hypertrophic/pathology/*surgery
MH  - Epidemiologic Methods
MH  - Female
MH  - Heart Septum/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2011/09/02 06:00
MHDA- 2011/12/21 06:00
CRDT- 2011/09/02 06:00
PHST- 2010/07/26 00:00 [received]
PHST- 2010/12/01 00:00 [accepted]
PHST- 2011/09/02 06:00 [entrez]
PHST- 2011/09/02 06:00 [pubmed]
PHST- 2011/12/21 06:00 [medline]
AID - S0102-76382011000100016 [pii]
AID - 10.1590/s0102-76382011000100016 [doi]
PST - ppublish
SO  - Rev Bras Cir Cardiovasc. 2011 Jan-Mar;26(1):86-92. doi: 
      10.1590/s0102-76382011000100016.