PMID- 21881861
OWN - NLM
STAT- MEDLINE
DCOM- 20120802
LR  - 20211020
IS  - 1573-2983 (Electronic)
IS  - 0269-4042 (Linking)
VI  - 34
IP  - 3
DP  - 2012 Jun
TI  - Residues of fluoroquinolones in marine aquaculture environment of the Pearl River 
      Delta, South China.
PG  - 323-35
LID - 10.1007/s10653-011-9420-4 [doi]
AB  - Concentrations and distributions of selected fluoroquinolones (norfloxacin, 
      ciprofloxacin and enrofloxacin) in water, sediments and nine kinds of fish 
      species collected from 6 sites in two marine aquaculture regions of the Pearl 
      River Delta, China, were analyzed by using high-performance liquid chromatography 
      with fluorescence detector (HPLC). The results showed that the concentrations of 
      ciprofloxacin and enrofloxacin were below the limits of quantification (LOQ) in 
      all water samples except for norfloxacin. Norfloxacin and ciprofloxacin 
      concentrations ranged from 1.88 to 11.20 ng g(-1) dry wt, 0.76-2.42 ng g(-1) dry 
      wt in sediments collected from the Dapeng'ao region (sites 1-3) and ranged from 
      2.31 to 4.75 ng g(-1) dry wt, 1.26-1.76 ng g(-1) dry wt in sediments collected 
      from the Hailing Island region (sites 4-6), respectively. However, no 
      enrofloxacin was found in all sediment samples. The three fluoroquinolones (FQs) 
      were detected in all fish samples, and the concentrations were higher in liver 
      tissues than those in muscle tissues. The levels of norfloxacin were higher than 
      ciprofloxacin and enrofloxacin in both liver and muscle tissues. Among the nine 
      marine fish species, Siganus fuscescens from Hailing Island had a significantly 
      high level of norfloxacin in liver tissue (254.58 ng g(-1) wet wt), followed by 
      Sparus macrocephalus (133.15 ng g(-1) wet wt) from Dapeng'ao, and the lowest 
      value was Lutianus argentimaculatus (5.18 ng g(-1) wet wt) from Hailing Island. 
      The obtained results of FQs in present study do not represent a risk to the human 
      health in Guangdong coastal area, based on the maximum residue limits (MRLs) 
      established by Chinese Government and the acceptable daily intake (ADI) 
      recommended by the Food and Agriculture Organization and World Health 
      Organization (FAO/WHO).
FAU - He, Xiuting
AU  - He X
AD  - Institute of Hydrobiology, Jinan University, Guangzhou, 510632, China.
FAU - Wang, Zhaohui
AU  - Wang Z
FAU - Nie, Xiangping
AU  - Nie X
FAU - Yang, Yufen
AU  - Yang Y
FAU - Pan, Debo
AU  - Pan D
FAU - Leung, Anna O W
AU  - Leung AO
FAU - Cheng, Zhang
AU  - Cheng Z
FAU - Yang, Yongtao
AU  - Yang Y
FAU - Li, Kaibin
AU  - Li K
FAU - Chen, Kunci
AU  - Chen K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110901
PL  - Netherlands
TA  - Environ Geochem Health
JT  - Environmental geochemistry and health
JID - 8903118
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Water Pollutants, Chemical)
RN  - 5E8K9I0O4U (Ciprofloxacin)
RN  - N0F8P22L1P (Norfloxacin)
SB  - IM
MH  - Animals
MH  - Anti-Infective Agents/*analysis/metabolism
MH  - China
MH  - Chromatography, High Pressure Liquid
MH  - Ciprofloxacin/*analysis/metabolism
MH  - Environmental Monitoring/standards
MH  - Geologic Sediments/analysis
MH  - Humans
MH  - Limit of Detection
MH  - Norfloxacin/*analysis/metabolism
MH  - Perciformes/*metabolism
MH  - Risk Assessment
MH  - Seawater/analysis
MH  - Species Specificity
MH  - Water Pollutants, Chemical/*analysis/metabolism
EDAT- 2011/09/02 06:00
MHDA- 2012/08/03 06:00
CRDT- 2011/09/02 06:00
PHST- 2011/04/15 00:00 [received]
PHST- 2011/08/04 00:00 [accepted]
PHST- 2011/09/02 06:00 [entrez]
PHST- 2011/09/02 06:00 [pubmed]
PHST- 2012/08/03 06:00 [medline]
AID - 10.1007/s10653-011-9420-4 [doi]
PST - ppublish
SO  - Environ Geochem Health. 2012 Jun;34(3):323-35. doi: 10.1007/s10653-011-9420-4. 
      Epub 2011 Sep 1.