PMID- 21892660
OWN - NLM
STAT- MEDLINE
DCOM- 20120724
LR  - 20220318
IS  - 1525-1497 (Electronic)
IS  - 0884-8734 (Print)
IS  - 0884-8734 (Linking)
VI  - 27
IP  - 3
DP  - 2012 Mar
TI  - Symptoms of anxiety and cardiac hospitalizations at 12 months in patients with 
      heart failure.
PG  - 345-50
LID - 10.1007/s11606-011-1843-1 [doi]
AB  - OBJECTIVE: Heart failure (HF) is a leading cause of hospitalization. Clinical and 
      socio-demographic factors have been associated with cardiac admissions, but 
      little is known about the role of anxiety. We examined whether symptoms of 
      anxiety were associated with cardiac hospitalizations at 12 months in HF 
      patients. METHODS: HF outpatients (N = 237) completed the Hospital Anxiety and 
      Depression Scale (HADS) at baseline (i.e., inclusion into the study). A cutoff >/=8 
      was used to indicate probable clinical levels of anxiety and depression. At 
      12 months, a medical chart abstraction was performed to obtain information on 
      cardiac hospitalizations. RESULTS: The prevalence of symptoms of anxiety was 
      24.9% (59/237), and 27.0% (64/237) of patients were admitted for cardiac reasons 
      at least once during the 12-month follow-up period. Symptoms of anxiety were 
      neither significantly associated with cardiac hospitalizations in univariable 
      logistic analysis [OR = 1.13, 95% CI (0.59-2.17), p = 0.72] nor in multivariable 
      analysis [OR = 0.94, 95% CI (0.38-2.31), p = 0.89]. New York Heart Association 
      (NYHA) functional class III [OR = 3.00, 95% CI (1.08-8.12), p = 0.04] and a 
      history of HF-related hospitalizations [OR = 1.18, 95% CI (1.01-1.38), p = 0.03] 
      were independently associated with 12-month cardiac admissions. CONCLUSIONS: The 
      current study found no significant association between symptoms of anxiety and 
      cardiac hospitalizations at 12 months in HF patients. In contrast, clinical 
      indicators (i.e., NYHA class III and a history of HF-related hospitalizations) 
      were significantly associated with admissions due to a cardiac cause. Future 
      studies are warranted to investigate the importance of symptoms of anxiety in HF 
      using a larger sample size and a longer follow-up duration.
FAU - Damen, Nikki L
AU  - Damen NL
AD  - Center of Research on Psychology in Somatic diseases (CoRPS), Department of 
      Medical Psychology, Tilburg University, P.O. Box 90153, 5000 LE, Tilburg, The 
      Netherlands.
FAU - Pelle, Aline J
AU  - Pelle AJ
FAU - Szabo, Balazs M
AU  - Szabo BM
FAU - Pedersen, Susanne S
AU  - Pedersen SS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20110903
PL  - United States
TA  - J Gen Intern Med
JT  - Journal of general internal medicine
JID - 8605834
SB  - IM
MH  - Aged
MH  - Anxiety/*epidemiology/etiology
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/complications/epidemiology/*therapy
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Male
MH  - Prevalence
MH  - Psychometrics/*methods
MH  - Retrospective Studies
MH  - United States/epidemiology
PMC - PMC3286556
COIS- None disclosed.
EDAT- 2011/09/06 06:00
MHDA- 2012/07/25 06:00
PMCR- 2011/09/03
CRDT- 2011/09/06 06:00
PHST- 2011/01/10 00:00 [received]
PHST- 2011/08/09 00:00 [accepted]
PHST- 2011/06/01 00:00 [revised]
PHST- 2011/09/06 06:00 [entrez]
PHST- 2011/09/06 06:00 [pubmed]
PHST- 2012/07/25 06:00 [medline]
PHST- 2011/09/03 00:00 [pmc-release]
AID - 1843 [pii]
AID - 10.1007/s11606-011-1843-1 [doi]
PST - ppublish
SO  - J Gen Intern Med. 2012 Mar;27(3):345-50. doi: 10.1007/s11606-011-1843-1. Epub 
      2011 Sep 3.