PMID- 21896634 OWN - NLM STAT- MEDLINE DCOM- 20120330 LR - 20220316 IS - 1464-3677 (Electronic) IS - 1353-4505 (Linking) VI - 23 IP - 6 DP - 2011 Dec TI - What makes hospitalized patients more vulnerable and increases their risk of experiencing an adverse event? PG - 705-12 LID - 10.1093/intqhc/mzr059 [doi] AB - OBJECTIVE: To analyze the relationship between the appearance of adverse events (AEs) and both patient comorbidities and the use of medical devices. DESIGN: Retrospective medical records review study. SETTING: Twenty-four Spanish public hospitals. PARTICIPANTS: Clinical records of 5624 discharged patients. MAIN OUTCOME MEASURE: Incidence of AEs. RESULTS: Patients aged >65 have 2.4 times the risk of experiencing an AE compared with those aged <65. The presence of certain comorbidities and devices (neoplasia, chronic hepatic alteration, cardiac insufficiency, coronary disease, high blood pressure, urethral catheterization, catheterization of a vessel, tracheostomy or stay of >7 days) were associated with developing an AE during hospitalization. There is a trend effect if we consider the number of comorbidities and the number of devices used. Thus, the risk of an AE in subjects who present no comorbidities was 3.2%, which rose to 9.9% in those with one intrinsic risk factor, 16.7% in those with two and 29.3% in those with three or more. Similarly, subjects without extrinsic risk factor experienced an AE in 4.4% of cases, which rose to 9.6% when there was one risk factor, to 13.4% when there were two and to 33.0% when there were three or more risk factors. The effect of some of these pathologies and that associated with age disappeared on adjusting in line with other variables. CONCLUSIONS: The true risk resides in the number of exposures to potentially iatrogenic actions, rather than being intrinsic to age or the presence of certain comorbidities. FAU - Aranaz-Andres, J M AU - Aranaz-Andres JM AD - Dpto. Salud Publica, Universidad Miguel Hernandez, Campus de San Juan, Carretera Alicante-Valencia Km. 8,7, 03550 San Juan de Alicante, Spain. aranaz_jes@gva.es FAU - Limon, R AU - Limon R FAU - Mira, J J AU - Mira JJ FAU - Aibar, C AU - Aibar C FAU - Gea, M T AU - Gea MT FAU - Agra, Y AU - Agra Y CN - ENEAS Working Group LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20110906 PL - England TA - Int J Qual Health Care JT - International journal for quality in health care : journal of the International Society for Quality in Health Care JID - 9434628 SB - IM MH - Aged MH - Comorbidity MH - Equipment and Supplies/adverse effects MH - Female MH - Humans MH - *Inpatients MH - Male MH - Medical Audit MH - *Medical Errors MH - Middle Aged MH - Quality of Health Care MH - Retrospective Studies MH - *Risk Assessment MH - Risk Factors MH - Safety Management MH - Spain FIR - Infante, A IR - Infante A FIR - Polo, M P IR - Polo MP FIR - Terol, E IR - Terol E FIR - Casal, J M IR - Casal JM FIR - Sierra, E IR - Sierra E FIR - Garcia, M J IR - Garcia MJ FIR - Agra, Y IR - Agra Y FIR - Palanca, I IR - Palanca I FIR - Vitaller, J IR - Vitaller J FIR - Zarco, A IR - Zarco A FIR - Soro, C IR - Soro C FIR - Ivorra, F M IR - Ivorra FM FIR - Bartolome, F IR - Bartolome F FIR - Gomez, J A IR - Gomez JA FIR - Agullo, V IR - Agullo V FIR - Montesinos, M A IR - Montesinos MA FIR - Garcia, J R IR - Garcia JR FIR - Aguado, L R IR - Aguado LR FIR - Cortes, M P IR - Cortes MP FIR - Misiego, A IR - Misiego A FIR - Jimenez, L IR - Jimenez L FIR - Villaverde, M V IR - Villaverde MV FIR - Abadia, M B IR - Abadia MB FIR - Ceballos, C IR - Ceballos C FIR - Garcia, E E IR - Garcia EE FIR - de la Hoz, C A IR - de la Hoz CA FIR - Jaen, P IR - Jaen P FIR - Lechuga, L IR - Lechuga L FIR - Rebull, J IR - Rebull J FIR - Brull, L l IR - Brull Ll FIR - Gombau, C IR - Gombau C FIR - Domenech, M F IR - Domenech MF FIR - Gomez, F IR - Gomez F FIR - Becerra, D IR - Becerra D FIR - Donate, C IR - Donate C FIR - Valero, C IR - Valero C FIR - Martinez, M D IR - Martinez MD FIR - Ansede, J C IR - Ansede JC FIR - Albeniz, C IR - Albeniz C FIR - Arias, S IR - Arias S FIR - Carrion, M IR - Carrion M FIR - Lobote, M IR - Lobote M FIR - Vadillo, P IR - Vadillo P FIR - Lameiro, F J IR - Lameiro FJ FIR - Jauregui, M A IR - Jauregui MA FIR - Sarasa, I IR - Sarasa I FIR - Silvestre, C IR - Silvestre C FIR - Cots, F IR - Cots F FIR - Lasso, C IR - Lasso C FIR - Garcia, P IR - Garcia P FIR - Bartolome, N IR - Bartolome N FIR - del Campo, V IR - del Campo V FIR - Felpeto, I IR - Felpeto I FIR - Guimarey, R M IR - Guimarey RM FIR - Homs, E IR - Homs E FIR - Durany, M IR - Durany M FIR - Quintana, M IR - Quintana M FIR - Monteis, J IR - Monteis J FIR - Valenzuela, J C IR - Valenzuela JC FIR - Diaz, M IR - Diaz M FIR - Calonge, M L IR - Calonge ML FIR - Valledor, M IR - Valledor M FIR - Martin, M T IR - Martin MT FIR - Jimenez, R M IR - Jimenez RM FIR - Cabrera, A IR - Cabrera A FIR - Murcia, M J IR - Murcia MJ FIR - Blasco, S IR - Blasco S FIR - Sanchez-Porro, A IR - Sanchez-Porro A FIR - Gamez, M V IR - Gamez MV FIR - Calle, F IR - Calle F FIR - Biurrun, A IR - Biurrun A FIR - Leon, E IR - Leon E FIR - Ovejero, A F IR - Ovejero AF FIR - Martinez, R IR - Martinez R FIR - Rivas, M IR - Rivas M FIR - Tormo, A IR - Tormo A FIR - Gomez-Alferez, C IR - Gomez-Alferez C FIR - Enriquez, F IR - Enriquez F FIR - Cabello, J A IR - Cabello JA FIR - Perez, D IR - Perez D FIR - Lopez, L IR - Lopez L FIR - Amor, J F IR - Amor JF FIR - Gomez, A IR - Gomez A FIR - Martinez, J IR - Martinez J FIR - Celorrio, J M IR - Celorrio JM FIR - Clemente, M E IR - Clemente ME FIR - Garcia, M C IR - Garcia MC FIR - Orobitg, J IR - Orobitg J FIR - Gaig, M T IR - Gaig MT FIR - Viciosa, M IR - Viciosa M FIR - Del Rio, P IR - Del Rio P FIR - Capetillo, M P IR - Capetillo MP FIR - Cuesta, S IR - Cuesta S FIR - Martinez, A IR - Martinez A FIR - Berrozpe, E M IR - Berrozpe EM FIR - Miralles, J J IR - Miralles JJ FIR - Garcia, R IR - Garcia R FIR - Fernandez, E IR - Fernandez E FIR - De la Tassa, J IR - De la Tassa J FIR - Barcelo, F X IR - Barcelo FX FIR - Garcia, P IR - Garcia P FIR - Herrera, P IR - Herrera P FIR - Fernandez, J IR - Fernandez J FIR - Garcia, J M IR - Garcia JM FIR - Torralba, L l IR - Torralba Ll FIR - Blanco, M A IR - Blanco MA FIR - Pajuelo, J M IR - Pajuelo JM FIR - Rey, J IR - Rey J FIR - Pardo, A IR - Pardo A FIR - Paredes, J IR - Paredes J FIR - Darpon, J IR - Darpon J FIR - Carreras, M IR - Carreras M FIR - Meneu, R IR - Meneu R EDAT- 2011/09/08 06:00 MHDA- 2012/03/31 06:00 CRDT- 2011/09/08 06:00 PHST- 2011/09/08 06:00 [entrez] PHST- 2011/09/08 06:00 [pubmed] PHST- 2012/03/31 06:00 [medline] AID - mzr059 [pii] AID - 10.1093/intqhc/mzr059 [doi] PST - ppublish SO - Int J Qual Health Care. 2011 Dec;23(6):705-12. doi: 10.1093/intqhc/mzr059. Epub 2011 Sep 6.