PMID- 21897895
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20111110
LR  - 20220316
IS  - 2230-9500 (Electronic)
IS  - 2230-8210 (Print)
IS  - 2230-9500 (Linking)
VI  - 15
IP  - 3
DP  - 2011 Jul
TI  - Diagnosis of gestational diabetes mellitus in Asian-Indian women.
PG  - 187-90
LID - 10.4103/2230-8210.83403 [doi]
AB  - OBJECTIVE: To assess the validity of Diabetes in Pregnancy Study Group India 
      (DIPSI) guidelines, a modified version of the WHO criterion to diagnose 
      gestational diabetes mellitus (GDM). MATERIALS AND METHODS: A total of 1 463 
      consecutive pregnant women in the second and third trimester of pregnancy 
      underwent 75 g oral glucose tolerance test (OGTT) and 2-h plasma glucose (PG) was 
      measured by the glucose oxidase-peroxidase (GOD-POD) method. GDM was diagnosed 
      with 2-h PG >/= 7.8 mmol/L (WHO criteria) and the rest were classified as normal 
      glucose tolerant (NGT) women. GDM women were advised medical nutrition therapy 
      (MNT) for two weeks. Those who failed to reach the target glycemic level of FPG < 
      5.0 mmol/L and 2-h PG < 6.67 mmol/L with MNT were advised insulin. All of them 
      were followed throughout pregnancy until delivery. Birth weight of 90th 
      percentile (> 3.45 kg) in the neonates was considered as macrosomia (primary 
      outcome). RESULTS: The mean maternal age and body mass index were 23.60+/-3.32 
      years and 21.5+/-4.06 kg/m(2) respectively. The mean gestational age was 27.9+/-5.56 
      weeks. DIPSI criterion identified 196 women (13.4%) as GDM and the rest as NGT. 
      Insulin was required in 19 (9.7%) women with GDM. Macrosomia was observed in 9.9% 
      GDM women with intervention and 9.8% in NGT (P = 1.000). CONCLUSION: DIPSI 
      criterion is a one step-cost effective and evidence-based procedure to diagnose 
      GDM in any socio-economic setting.
FAU - Balaji, V
AU  - Balaji V
AD  - Clinical Epidemiology Division, Dr. V. Seshiah Diabetes Research Institute, Dr. 
      Balaji Diabetes Care Centre, Aminjikarai, Chennai, India.
FAU - Balaji, Madhuri
AU  - Balaji M
FAU - Anjalakshi, C
AU  - Anjalakshi C
FAU - Cynthia, A
AU  - Cynthia A
FAU - Arthi, T
AU  - Arthi T
FAU - Seshiah, V
AU  - Seshiah V
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Endocrinol Metab
JT  - Indian journal of endocrinology and metabolism
JID - 101555690
PMC - PMC3156538
OTO - NOTNLM
OT  - Diabetes in pregnancy study group India
OT  - World Health Organization
OT  - gestational diabetes mellitus
COIS- Conflict of Interest: None declared.
EDAT- 2011/09/08 06:00
MHDA- 2011/09/08 06:01
PMCR- 2011/07/01
CRDT- 2011/09/08 06:00
PHST- 2011/09/08 06:00 [entrez]
PHST- 2011/09/08 06:00 [pubmed]
PHST- 2011/09/08 06:01 [medline]
PHST- 2011/07/01 00:00 [pmc-release]
AID - IJEM-15-187 [pii]
AID - 10.4103/2230-8210.83403 [doi]
PST - ppublish
SO  - Indian J Endocrinol Metab. 2011 Jul;15(3):187-90. doi: 10.4103/2230-8210.83403.