PMID- 21898904
OWN - NLM
STAT- MEDLINE
DCOM- 20111227
LR  - 20110907
IS  - 1526-4998 (Electronic)
IS  - 1526-498X (Linking)
VI  - 67
IP  - 10
DP  - 2011 Oct
TI  - The impact of altered herbicide residues in transgenic herbicide-resistant crops 
      on standard setting for herbicide residues.
PG  - 1193-210
LID - 10.1002/ps.2128 [doi]
AB  - The global area covered with transgenic (genetically modified) crops has rapidly 
      increased since their introduction in the mid-1990s. Most of these crops have 
      been rendered herbicide resistant, for which it can be envisaged that the 
      modification has an impact on the profile and level of herbicide residues within 
      these crops. In this article, the four main categories of herbicide resistance, 
      including resistance to acetolactate-synthase inhibitors, bromoxynil, glufosinate 
      and glyphosate, are reviewed. The topics considered are the molecular mechanism 
      underlying the herbicide resistance, the nature and levels of the residues formed 
      and their impact on the residue definition and maximum residue limits (MRLs) 
      defined by the Codex Alimentarius Commission and national authorities. No general 
      conclusions can be drawn concerning the nature and level of residues, which has 
      to be done on a case-by-case basis. International residue definitions and MRLs 
      are still lacking for some herbicide-crop combinations, and harmonisation is 
      therefore recommended.
CI  - Copyright (c) 2011 Society of Chemical Industry.
FAU - Kleter, Gijs A
AU  - Kleter GA
AD  - RIKILT-Institute of Food Safety, Wageningen University and Research Centre, 
      Wageningen, Holland. gijs.kleter@wur.nl
FAU - Unsworth, John B
AU  - Unsworth JB
FAU - Harris, Caroline A
AU  - Harris CA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20110830
PL  - England
TA  - Pest Manag Sci
JT  - Pest management science
JID - 100898744
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Crops, Agricultural/*genetics/metabolism
MH  - *Herbicide Resistance
MH  - *Pesticide Residues
MH  - Plants, Genetically Modified/*metabolism
EDAT- 2011/09/08 06:00
MHDA- 2011/12/28 06:00
CRDT- 2011/09/08 06:00
PHST- 2010/12/12 00:00 [received]
PHST- 2011/01/04 00:00 [accepted]
PHST- 2011/09/08 06:00 [entrez]
PHST- 2011/09/08 06:00 [pubmed]
PHST- 2011/12/28 06:00 [medline]
AID - 10.1002/ps.2128 [doi]
PST - ppublish
SO  - Pest Manag Sci. 2011 Oct;67(10):1193-210. doi: 10.1002/ps.2128. Epub 2011 Aug 30.