PMID- 21911428
OWN - NLM
STAT- MEDLINE
DCOM- 20121017
LR  - 20170919
IS  - 1477-0393 (Electronic)
IS  - 0748-2337 (Linking)
VI  - 28
IP  - 4
DP  - 2012 May
TI  - The first application of a new polysaccharide from Acanthophyllum bracteatum for 
      the health improvement of Atlantic salmon exposed to mercury chloride.
PG  - 377-84
LID - 10.1177/0748233711413797 [doi]
AB  - Polysaccharides are biopolymers that play key roles as therapeutic agents. The 
      current study examined the efficiency of a polysaccharide newly derived from a 
      plant resource for detection of sub-acute mercury (Hg) exposure on blood 
      characteristics of Atlantic salmon. The polysaccharide was extracted from the 
      roots of Acanthophyllum bracteatum, and the Atlantic salmon were divided into 
      three groups and placed in fiberglass tanks: one with no Hg as a control, one 
      filled with 60 microg l(-1) of Hg solution, and one with 60 microg l(-1) Hg solution plus 
      1% weight/weight (w/w) of polysaccharide, which had been added 24 hours before 
      the addition of Hg solution. Serum hematological and biochemical parameters were 
      analysed. Results of the study showed that the blood factors were significantly 
      adjusted in the group that had been exposed to the polysaccharide and Hg compared 
      to the group that had been exposed only to Hg. The polysaccharide had an 
      adjustment effect on lymphocytes, granulocytes, red blood cells (RBCs), 
      Hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin 
      (MCH), alanine aminotransferase (ALT), aspartate aminotransferase (AST), protein, 
      chlorine (Cl), sodium (Na), and glucose. It did not have a significant effect on 
      hematocrit (Ht), mean corpuscular hemoglobin concentration (MCHC), potassium (K), 
      and monocytes. Finally, the results confirmed that the new polysaccharide has 
      useful effects on the host, possibly acting as a probiotic by selectively 
      motivating the activity of some useful bacteria, which can improve the host 
      health. This is the first report on application of this polysaccharide for the 
      health improvement of Atlantic salmon exposed to mercury chloride.
FAU - Jahanbin, Kambiz
AU  - Jahanbin K
AD  - Faculty of Agriculture, School of Agricultural Engineering, Shahrood University 
      of Technology, Shahrood, Iran.
FAU - Hedayati, Aliakbar
AU  - Hedayati A
FAU - Moini, Sohrab
AU  - Moini S
FAU - Gohari, Ahmad Reza
AU  - Gohari AR
FAU - Emam-Djomeh, Zahra
AU  - Emam-Djomeh Z
FAU - Esposito, Antonio
AU  - Esposito A
FAU - Bagheri, Tahere
AU  - Bagheri T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Retracted Publication
DEP - 20110912
PL  - England
TA  - Toxicol Ind Health
JT  - Toxicology and industrial health
JID - 8602702
RN  - 0 (Plant Extracts)
RN  - 0 (Polysaccharides)
RN  - 0 (Protective Agents)
RN  - 059QF0KO0R (Water)
RN  - 53GH7MZT1R (Mercuric Chloride)
RN  - FXS1BY2PGL (Mercury)
SB  - IM
RIN - Toxicol Ind Health. 2017 Jan;33(1):NP1. PMID: 28092234
MH  - Analysis of Variance
MH  - Animals
MH  - Blood/drug effects
MH  - Blood Cells/cytology/drug effects
MH  - Blood Chemical Analysis
MH  - Caryophyllaceae/*chemistry
MH  - Fish Diseases/blood/chemically induced/*drug therapy
MH  - Leukocyte Count
MH  - Liver/chemistry
MH  - Mercuric Chloride/*toxicity
MH  - Mercury/analysis/blood
MH  - Plant Extracts/*pharmacology
MH  - Plant Roots/chemistry
MH  - Polysaccharides/*pharmacology
MH  - Protective Agents/pharmacology
MH  - Random Allocation
MH  - *Salmo salar
MH  - Water/chemistry
EDAT- 2011/09/14 06:00
MHDA- 2012/10/18 06:00
CRDT- 2011/09/14 06:00
PHST- 2011/09/14 06:00 [entrez]
PHST- 2011/09/14 06:00 [pubmed]
PHST- 2012/10/18 06:00 [medline]
AID - 0748233711413797 [pii]
AID - 10.1177/0748233711413797 [doi]
PST - ppublish
SO  - Toxicol Ind Health. 2012 May;28(4):377-84. doi: 10.1177/0748233711413797. Epub 
      2011 Sep 12.