PMID- 21913518
OWN - NLM
STAT- MEDLINE
DCOM- 20111005
LR  - 20110914
IS  - 0189-2657 (Print)
IS  - 0189-2657 (Linking)
VI  - 21
IP  - 2
DP  - 2011 Apr-Jun
TI  - Pesticide residue levels in maize samples from markets in Lagos State, Nigeria.
PG  - 169-74
AB  - BACKGROUND: Pesticides are used widely in agriculture to control destructive 
      pests and hence increase food supply. Their use inadvertently leads to residues 
      in food crops and the environment. Pesticides, by nature are poisonous and 
      exposure of humans to their residues may cause health hazards which include 
      neurotoxicity and carcinogenicity among others. Evaluation of pesticide residues 
      in food is therefore of public health importance and would help to ensure that 
      levels are kept within safety limits. OBJECTIVE: The aim of this study was to 
      determine the incidence and quantity of organochlorine pesticide residues in 
      maize samples collected from various markets in Lagos State and compare values 
      obtained with established safety values in order to highlight possible health 
      hazards. METHODS: In this study, samples of white maize (Zea mays L.) purchased 
      from different markets in Lagos State were analyzed for residues of 
      organochlorine pesticides using gas chromatograph with mass spectrometric 
      detector (GC-MS) after careful extraction and cleanup. RESULTS: The results 
      showed that 96% of the maize samples contained residues of one or more 
      organochlorine pesticides. Mean concentrations ranged from 7.9-52.0 microg/kg and 
      maximum residue limits (MRLs) of some pesticides were exceeded in up to 7% of 
      samples. The estimated total diet intakes (ETDIs) for aldrin and dieldrin 
      exceeded their maximum permissible intakes. CONCLUSION: It is concluded that 
      residues of organochlorine pesticides are present in maize in Lagos markets. Some 
      exceed safety levels with possible adverse effects on human health. There is 
      therefore a need for more stringent monitoring of the use of pesticides in 
      agriculture and food storage in Nigeria.
FAU - Ogah, C O
AU  - Ogah CO
AD  - Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Lagos, 
      Nigeria. onotsec@yahoo.com
FAU - Coker, H A B
AU  - Coker HA
FAU - Adepoju-Bello, A A
AU  - Adepoju-Bello AA
LA  - eng
PT  - Journal Article
PL  - Nigeria
TA  - Nig Q J Hosp Med
JT  - Nigerian quarterly journal of hospital medicine
JID - 9713944
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Agriculture
MH  - Food Contamination/*analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*analysis
MH  - Nigeria
MH  - Pesticide Residues/adverse effects/*analysis
MH  - Public Health
MH  - *Zea mays
EDAT- 2011/09/15 06:00
MHDA- 2011/10/06 06:00
CRDT- 2011/09/15 06:00
PHST- 2011/09/15 06:00 [entrez]
PHST- 2011/09/15 06:00 [pubmed]
PHST- 2011/10/06 06:00 [medline]
PST - ppublish
SO  - Nig Q J Hosp Med. 2011 Apr-Jun;21(2):169-74.