PMID- 21914156
OWN - NLM
STAT- MEDLINE
DCOM- 20120116
LR  - 20221207
IS  - 1346-8138 (Electronic)
IS  - 0385-2407 (Linking)
VI  - 38
IP  - 6
DP  - 2011 Jun
TI  - Development of Behcet's disease in a Caucasian with human leukocyte antigen B51 
      after immigration to Japan.
PG  - 581-4
LID - 10.1111/j.1346-8138.2010.01125.x [doi]
AB  - We herein report a 32-year-old Caucasian woman with human leukocyte antigen 
      (HLA)-B51 who developed Behcet's disease after immigration to Japan. She was born 
      and raised in Finland and had never experienced any clinical symptoms related to 
      Behcet's disease before immigration to Japan. None of her family members in 
      Finland had similar problems. Two years after the immigration, she developed 
      typical clinical symptoms of Behcet's disease. This report strongly supports the 
      canonical notion that the interaction of genetic factors, such as HLA-B51, with 
      environmental factors specific to the countries in the Silk Road area, including 
      Japan, may play a pivotal role in the pathogenesis of this disorder.
CI  - (c) 2010 Japanese Dermatological Association.
FAU - Kimura, Takayuki
AU  - Kimura T
AD  - Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, 
      Japan.
FAU - Asano, Yoshihide
AU  - Asano Y
FAU - Yamamoto, Mizuho
AU  - Yamamoto M
FAU - Sugaya, Makoto
AU  - Sugaya M
FAU - Sato, Shinichi
AU  - Sato S
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20101213
PL  - England
TA  - J Dermatol
JT  - The Journal of dermatology
JID - 7600545
RN  - 0 (HLA-B51 Antigen)
SB  - IM
MH  - Adult
MH  - Behcet Syndrome/*diagnosis/etiology/*immunology
MH  - Emigration and Immigration
MH  - Female
MH  - Finland/ethnology
MH  - HLA-B51 Antigen/*genetics
MH  - Humans
MH  - Japan
MH  - White People
EDAT- 2011/09/15 06:00
MHDA- 2012/01/17 06:00
CRDT- 2011/09/15 06:00
PHST- 2011/09/15 06:00 [entrez]
PHST- 2011/09/15 06:00 [pubmed]
PHST- 2012/01/17 06:00 [medline]
AID - 10.1111/j.1346-8138.2010.01125.x [doi]
PST - ppublish
SO  - J Dermatol. 2011 Jun;38(6):581-4. doi: 10.1111/j.1346-8138.2010.01125.x. Epub 
      2010 Dec 13.