PMID- 21916988
OWN - NLM
STAT- MEDLINE
DCOM- 20120806
LR  - 20220408
IS  - 1440-1746 (Electronic)
IS  - 0815-9319 (Linking)
VI  - 27
IP  - 4
DP  - 2012 Apr
TI  - Prevalence of gastroesophageal reflux disease in Korea and associated health-care 
      utilization: a national population-based study.
PG  - 741-5
LID - 10.1111/j.1440-1746.2011.06921.x [doi]
AB  - BACKGROUND AND AIM: Few studies have reported temporal trends in the prevalence 
      of gastroesophageal reflux disease (GERD) and associated health-care utilization 
      in Asia. The aim of this study was to investigate temporal changes in the 
      prevalence of GERD and associated health-care utilization. METHODS: Patients with 
      a primary or secondary disease code for GERD, according to the Korean Standard 
      Classification of Diseases, were defined as having "doctor-diagnosed GERD". The 
      prevalence of GERD from 2005 to 2008 was evaluated using Korean National Health 
      Insurance claim data. Claims for proton pump inhibitors (PPI) over this period 
      were also evaluated. Complications of GERD and health-care utilization 
      characteristics, such as the use of diagnostic tests and prescriptions, were 
      investigated. RESULTS: The prevalence of doctor-diagnosed GERD increased rapidly 
      from 4.6% to 7.3% between 2005 and 2008. Over the same period, the amount of PPI 
      claims increased by 56%. People aged 30-39 years and females had a high frequency 
      of GERD-related visits. Esophageal stricture was rare, and 23% of patients with 
      GERD had peptic ulcers. Endoscopy was used as a diagnostic test in 34% of cases. 
      Seventy-seven percent of patients with GERD were treated with PPI or H(2) 
      receptor antagonists. CONCLUSIONS: The prevalence of GERD increased rapidly from 
      2005 to 2008. The rapid increase of PPI use reflects the real increase in the 
      prevalence of GERD and demand for health care. Middle-aged people and women had a 
      high frequency of GERD visits. Therefore, GERD might be a significant disease 
      burden in Korea.
CI  - (c) 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell 
      Publishing Asia Pty Ltd.
FAU - Kim, Kyoung-Min
AU  - Kim KM
AD  - Health Insurance Review and Assessment Service, Research and Development Center, 
      Seoul, Korea.
FAU - Cho, Yu Kyung
AU  - Cho YK
FAU - Bae, Seung Jin
AU  - Bae SJ
FAU - Kim, Dong-Sook
AU  - Kim DS
FAU - Shim, Ki-Nam
AU  - Shim KN
FAU - Kim, Jie-Hyun
AU  - Kim JH
FAU - Jung, Sung Woo
AU  - Jung SW
FAU - Kim, Nayoung
AU  - Kim N
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - J Gastroenterol Hepatol
JT  - Journal of gastroenterology and hepatology
JID - 8607909
RN  - 0 (Histamine H2 Antagonists)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Esophageal Stenosis/complications/epidemiology
MH  - Esophagoscopy/statistics & numerical data
MH  - Female
MH  - Gastroesophageal Reflux/complications/*drug therapy/*epidemiology
MH  - Histamine H2 Antagonists/therapeutic use
MH  - Humans
MH  - Insurance, Health/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Patient Care/*statistics & numerical data/trends
MH  - Peptic Ulcer/complications/epidemiology
MH  - Prevalence
MH  - Proton Pump Inhibitors/*therapeutic use
MH  - Republic of Korea/epidemiology
MH  - Sex Factors
MH  - Young Adult
EDAT- 2011/09/16 06:00
MHDA- 2012/08/07 06:00
CRDT- 2011/09/16 06:00
PHST- 2011/09/16 06:00 [entrez]
PHST- 2011/09/16 06:00 [pubmed]
PHST- 2012/08/07 06:00 [medline]
AID - 10.1111/j.1440-1746.2011.06921.x [doi]
PST - ppublish
SO  - J Gastroenterol Hepatol. 2012 Apr;27(4):741-5. doi: 
      10.1111/j.1440-1746.2011.06921.x.