PMID- 21917768
OWN - NLM
STAT- MEDLINE
DCOM- 20111115
LR  - 20220316
IS  - 1526-632X (Electronic)
IS  - 0028-3878 (Linking)
VI  - 77
IP  - 13
DP  - 2011 Sep 27
TI  - Safety of spinal angiography: complication rate analysis in 302 diagnostic 
      angiograms.
PG  - 1235-40
LID - 10.1212/WNL.0b013e3182302068 [doi]
AB  - OBJECTIVE: Spinal digital subtraction angiography (SpDSA) continues to be the 
      imaging gold standard for the evaluation of spinal cord vascular disorders. The 
      safety of this procedure has a poor historical reputation and there are few 
      current reports on complication rates. We hypothesized that modern SpDSA can be 
      performed with an acceptably low risk of iatrogenic complications. METHODS: In 
      this retrospective series, we reviewed 302 consecutive spinal angiograms 
      performed during a 10-year period at our institution for the frequency of 
      intraprocedural and postprocedural neurologic, non-neurologic, and local 
      complications. Indications for SpDSA, prior noninvasive imaging findings, and 
      angiographic diagnoses for each case were assessed to evaluate the diagnostic 
      contribution of the procedure. RESULTS: There were no intraprocedural or 
      postprocedural neurologic complications in the studied cohort. Systemic 
      complications occurred in 2 cases (0.7%), in the form of back spasms in one 
      patient and pulmonary edema in the other. Both recovered promptly and were 
      discharged at baseline status. Access-site complications included 3 groin 
      hematomas (1.0%), all managed conservatively. MRI findings showed 51% sensitivity 
      and 83% specificity for spinal vascular malformations. A total of 31% of patients 
      with the preangiographic diagnosis of transverse myelitis were found to have a 
      vascular malformation. CONCLUSION: SpDSA carries very low risks of neurologic and 
      systemic complications, while offering a gold-standard level of diagnostic 
      confidence for the evaluation of the normal and pathologic vasculature of the 
      spinal cord.
FAU - Chen, James
AU  - Chen J
AD  - Nelson Building B-100, 600 N. Wolfe St, Johns Hopkins Hospital, Baltimore, MD 
      21287, USA.
FAU - Gailloud, Philippe
AU  - Gailloud P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110914
PL  - United States
TA  - Neurology
JT  - Neurology
JID - 0401060
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Angiography, Digital Subtraction/*adverse effects/statistics & numerical data
MH  - Central Nervous System Vascular Malformations/complications/diagnostic imaging
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Infant
MH  - Longitudinal Studies
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Spinal Cord/*diagnostic imaging/pathology
MH  - Spinal Cord Diseases/classification/*diagnosis
MH  - Vertebral Artery/diagnostic imaging/pathology
MH  - Young Adult
EDAT- 2011/09/16 06:00
MHDA- 2011/11/16 06:00
CRDT- 2011/09/16 06:00
PHST- 2011/09/16 06:00 [entrez]
PHST- 2011/09/16 06:00 [pubmed]
PHST- 2011/11/16 06:00 [medline]
AID - WNL.0b013e3182302068 [pii]
AID - 10.1212/WNL.0b013e3182302068 [doi]
PST - ppublish
SO  - Neurology. 2011 Sep 27;77(13):1235-40. doi: 10.1212/WNL.0b013e3182302068. Epub 
      2011 Sep 14.