PMID- 21921583
OWN - NLM
STAT- MEDLINE
DCOM- 20120105
LR  - 20211020
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Print)
IS  - 1424-8581 (Linking)
VI  - 135
IP  - 2
DP  - 2011
TI  - Karyotype differentiation between two stickleback species (Gasterosteidae).
PG  - 150-9
LID - 10.1159/000331232 [doi]
AB  - The stickleback family (Gasterosteidae) of fish is less than 40 million years 
      old, yet stickleback species have diverged in both diploid chromosome number (2n) 
      and morphology. We used comparative fluorescence in situ hybridization (FISH) on 
      2 stickleback species, Gasterosteus aculeatus (2n = 42) and Apeltes quadracus (2n 
      = 46), to ascertain the types of chromosome rearrangements that differentiate 
      these species. The A. quadracus karyotype contains more acrocentric and 
      telocentric chromosomes than the G. aculeatus karyotype. By using bacterial 
      artificial chromosome probes from G. aculeatus in our FISH screen, we found that 
      6 pericentric inversions and 2 chromosome fusions/fissions are responsible for 
      the greater number of acrocentric and telocentric chromosomes in A. quadracus. 
      While most populations of G. aculeatus have an XX/XY sex chromosome system, A. 
      quadracus has a ZZ/ZW sex chromosome system, as previously reported. However, we 
      discovered that a population of A. quadracus from Connecticut lacks heteromorphic 
      sex chromosomes, providing evidence for unexpected sex chromosome diversity in 
      this species.
CI  - Copyright (c) 2011 S. Karger AG, Basel.
FAU - Urton, J R
AU  - Urton JR
AD  - Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 
      98109-1024, USA.
FAU - McCann, S R
AU  - McCann SR
FAU - Peichel, C L
AU  - Peichel CL
LA  - eng
GR  - R01 GM089733/GM/NIGMS NIH HHS/United States
GR  - T32 HG000035/HG/NHGRI NIH HHS/United States
GR  - R01 GM071854/GM/NIGMS NIH HHS/United States
GR  - T32 HG00035/HG/NHGRI NIH HHS/United States
GR  - P50 HG002568/HG/NHGRI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20110913
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
SB  - IM
MH  - Animals
MH  - Centromere/*genetics
MH  - *Chromosome Inversion
MH  - Chromosomes/*genetics
MH  - Diploidy
MH  - Female
MH  - Genetic Variation
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotype
MH  - Male
MH  - Phylogeny
MH  - Sex Chromosomes/genetics
MH  - Smegmamorpha/classification/*genetics
MH  - Species Specificity
MH  - Spectral Karyotyping
PMC - PMC3224509
EDAT- 2011/09/17 06:00
MHDA- 2012/01/06 06:00
PMCR- 2012/10/01
CRDT- 2011/09/17 06:00
PHST- 2011/07/04 00:00 [accepted]
PHST- 2011/09/17 06:00 [entrez]
PHST- 2011/09/17 06:00 [pubmed]
PHST- 2012/01/06 06:00 [medline]
PHST- 2012/10/01 00:00 [pmc-release]
AID - 000331232 [pii]
AID - cgr0135-0150 [pii]
AID - 10.1159/000331232 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2011;135(2):150-9. doi: 10.1159/000331232. Epub 2011 Sep 
      13.