PMID- 21924924
OWN - NLM
STAT- MEDLINE
DCOM- 20120326
LR  - 20230425
IS  - 1096-3618 (Electronic)
IS  - 1044-5323 (Print)
IS  - 1044-5323 (Linking)
VI  - 23
IP  - 5
DP  - 2011 Oct
TI  - Transcription factor networks in dendritic cell development.
PG  - 388-97
LID - 10.1016/j.smim.2011.08.009 [doi]
AB  - Dendritic cells (DCs) are a heterogeneous population within the mononuclear 
      phagocyte system (MPS) that derive from bone marrow precursors. Commitment and 
      specification of hematopoietic progenitors to the DC lineage is critical for the 
      proper induction of both immunity and tolerance. This review summarizes the 
      important cytokines and transcription factors required for differentiation of the 
      DC lineage as well as further diversification into specific DC subsets. We 
      highlight recent advances in the characterization of immediate DC precursors 
      arising from the common myeloid progenitor (CMP). Particular emphasis is placed 
      on the corresponding temporal expression of relevant factors involved in 
      regulating developmental options.
CI  - 2011 Elsevier Ltd. All rights reserved.
FAU - Satpathy, Ansuman T
AU  - Satpathy AT
AD  - Department of Pathology and Immunology, Washington University School of Medicine, 
      660 S. Euclid Ave., St. Louis, MO 63110, USA.
FAU - Murphy, Kenneth M
AU  - Murphy KM
FAU - KC, Wumesh
AU  - KC W
LA  - eng
GR  - HHMI_/Howard Hughes Medical Institute/United States
PT  - Journal Article
PT  - Review
DEP - 20110915
PL  - England
TA  - Semin Immunol
JT  - Seminars in immunology
JID - 9009458
RN  - 0 (Transcription Factors)
SB  - IM
MH  - *Cell Differentiation
MH  - Cell Lineage
MH  - Dendritic Cells/*cytology
MH  - Humans
MH  - Models, Biological
MH  - Transcription Factors/*metabolism
PMC - PMC4010935
MID - NIHMS576202
OID - NLM: HHMIMS576202
EDAT- 2011/09/20 06:00
MHDA- 2012/03/27 06:00
PMCR- 2014/05/06
CRDT- 2011/09/20 06:00
PHST- 2011/02/04 00:00 [received]
PHST- 2011/08/19 00:00 [accepted]
PHST- 2011/09/20 06:00 [entrez]
PHST- 2011/09/20 06:00 [pubmed]
PHST- 2012/03/27 06:00 [medline]
PHST- 2014/05/06 00:00 [pmc-release]
AID - S1044-5323(11)00085-6 [pii]
AID - 10.1016/j.smim.2011.08.009 [doi]
PST - ppublish
SO  - Semin Immunol. 2011 Oct;23(5):388-97. doi: 10.1016/j.smim.2011.08.009. Epub 2011 
      Sep 15.