PMID- 21924999 OWN - NLM STAT- MEDLINE DCOM- 20120125 LR - 20110919 IS - 1558-0520 (Electronic) IS - 0733-8635 (Linking) VI - 29 IP - 4 DP - 2011 Oct TI - The use of intravenous immunoglobulin in autoimmune bullous diseases. PG - 565-70 LID - 10.1016/j.det.2011.06.010 [doi] AB - Intravenous immunoglobulin (IVIG) has been shown to be effective in the treatment of autoimmune blistering diseases and may be an option if disease is refractory to conventional treatment. IVIG effectiveness appears to increase when administered concurrently with a cytotoxic drug and used in multiple treatment cycles (though a single cycle may give benefit). Tapering administration may improve the duration of remission and subcutaneous injections may be an option. This article provides an introduction to the make-up and use of IVIG, and reviews previous studies. CI - Copyright (c) 2011 Elsevier Inc. All rights reserved. FAU - Chee, Shien-Ning AU - Chee SN AD - Department of Dermatology, St George Hospital, Gray Street, Kogarah, Sydney, NSW 2217, Australia. FAU - Murrell, Dedee F AU - Murrell DF LA - eng PT - Journal Article PT - Review DEP - 20110803 PL - United States TA - Dermatol Clin JT - Dermatologic clinics JID - 8300886 RN - 0 (Adrenal Cortex Hormones) RN - 0 (Dermatologic Agents) RN - 0 (Immunoglobulins, Intravenous) RN - 0 (Immunologic Factors) SB - IM MH - Adrenal Cortex Hormones/therapeutic use MH - Dermatologic Agents/therapeutic use MH - Female MH - Humans MH - Immunoglobulins, Intravenous/*therapeutic use MH - Immunologic Factors/*therapeutic use MH - Male MH - Randomized Controlled Trials as Topic MH - Skin Diseases, Vesiculobullous/*drug therapy MH - Treatment Outcome EDAT- 2011/09/20 06:00 MHDA- 2012/01/26 06:00 CRDT- 2011/09/20 06:00 PHST- 2011/09/20 06:00 [entrez] PHST- 2011/09/20 06:00 [pubmed] PHST- 2012/01/26 06:00 [medline] AID - S0733-8635(11)00118-5 [pii] AID - 10.1016/j.det.2011.06.010 [doi] PST - ppublish SO - Dermatol Clin. 2011 Oct;29(4):565-70. doi: 10.1016/j.det.2011.06.010. Epub 2011 Aug 3.