PMID- 21925943
OWN - NLM
STAT- MEDLINE
DCOM- 20120308
LR  - 20220331
IS  - 1878-5506 (Electronic)
IS  - 1389-9457 (Linking)
VI  - 12
IP  - 9
DP  - 2011 Oct
TI  - Insomnia characteristics and clinical correlates in Operation Enduring 
      Freedom/Operation Iraqi Freedom veterans with post-traumatic stress disorder and 
      mild traumatic brain injury: an exploratory study.
PG  - 850-9
LID - 10.1016/j.sleep.2011.06.004 [doi]
AB  - BACKGROUND: There is limited data on chronic insomnia in Operation Enduring 
      Freedom/Operation Iraqi Freedom (OEF/OIF) veterans, in whom post-traumatic stress 
      disorder (PTSD) and mild traumatic brain injury (mTBI) often co-exist. Our aim 
      was to compare sleep characteristics of three groups of OEF/OIF veterans: (1) 
      healthy sleepers (HS), (2) those with insomnia associated with PTSD and mTBI 
      (PTSD-mTBI), and (3) those with insomnia associated with PTSD alone. METHODS: 
      Consecutive veterans with insomnia complaints (> 6 months) were recruited over 6 
      months from the Miami VA Post Deployment clinic. Participants completed a sleep 
      disorders clinical interview, medical history, and questionnaires about insomnia, 
      sleepiness, pain, fatigue, depression, PTSD, and health-related quality of life. 
      They underwent polysomnography (PSG) with 2 weeks of actigraphy (ACT) and sleep 
      diaries. RESULTS: There were no differences in demographics or most questionnaire 
      responses between PTSD and PTSD-mTBI groups. Subjective daytime sleepiness was 
      significantly greater in PTSD-mTBI subjects compared with HS and PTSD 
      participants. Significant co-morbid sleep disorders were noted in insomnia 
      patients. PSG and ACT wake after sleep onset was significantly shorter in 
      PTSD-mTBI subjects as compared with PTSD participants. CONCLUSION: Insomnia 
      patients with PTSD-mTBI were subjectively sleepier despite spending less time 
      awake during the night than PTSD subjects, possibly as a consequence of head 
      trauma.
CI  - Published by Elsevier B.V.
FAU - Wallace, D M
AU  - Wallace DM
AD  - Department of Neurology, University of Miami Miller School of Medicine, Miami, 
      FL, USA. dwallace@med.miami.edu
FAU - Shafazand, S
AU  - Shafazand S
FAU - Ramos, A R
AU  - Ramos AR
FAU - Carvalho, D Z
AU  - Carvalho DZ
FAU - Gardener, H
AU  - Gardener H
FAU - Lorenzo, D
AU  - Lorenzo D
FAU - Wohlgemuth, W K
AU  - Wohlgemuth WK
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20110916
PL  - Netherlands
TA  - Sleep Med
JT  - Sleep medicine
JID - 100898759
SB  - IM
MH  - Actigraphy
MH  - Adolescent
MH  - Adult
MH  - Brain Injuries/*epidemiology
MH  - Comorbidity
MH  - Depression/epidemiology
MH  - Fatigue/epidemiology
MH  - Health Status
MH  - Humans
MH  - *Iraq War, 2003-2011
MH  - Male
MH  - Pain/epidemiology
MH  - Severity of Illness Index
MH  - Sleep Initiation and Maintenance Disorders/*diagnosis/*epidemiology
MH  - Stress Disorders, Post-Traumatic/*epidemiology
MH  - Surveys and Questionnaires
MH  - Veterans/*statistics & numerical data
MH  - Young Adult
EDAT- 2011/09/20 06:00
MHDA- 2012/03/09 06:00
CRDT- 2011/09/20 06:00
PHST- 2011/04/06 00:00 [received]
PHST- 2011/05/20 00:00 [revised]
PHST- 2011/06/01 00:00 [accepted]
PHST- 2011/09/20 06:00 [entrez]
PHST- 2011/09/20 06:00 [pubmed]
PHST- 2012/03/09 06:00 [medline]
AID - S1389-9457(11)00219-X [pii]
AID - 10.1016/j.sleep.2011.06.004 [doi]
PST - ppublish
SO  - Sleep Med. 2011 Oct;12(9):850-9. doi: 10.1016/j.sleep.2011.06.004. Epub 2011 Sep 
      16.