PMID- 21928203
OWN - NLM
STAT- MEDLINE
DCOM- 20120125
LR  - 20220321
IS  - 1897-4279 (Electronic)
IS  - 0022-9032 (Linking)
VI  - 69
IP  - 9
DP  - 2011
TI  - The value of ECG parameters in estimating myocardial injury and establishing 
      prognosis in patients with acute pulmonary embolism.
PG  - 933-8
AB  - BACKGROUND: The electrocardiogram (ECG) is characterised by little sensitivity 
      and specificity in the diagnostic evaluation of acute pulmonary embolism (APE). 
      AIM: To assess the significance of ECG changes in predicting myocardial injury 
      and prognosis in patients with APE. METHODS: The study group consisted of 225 
      patients (137 women and 88 men), mean age: 66.0 +/- 15.2 years, in whom the 
      diagnosis of APE was made, mostly based on computed tomography (n = 206, 92%). 
      RESULTS: We observed 26 in-hospital deaths (mortality rate: 11.5%) and 
      complications occurred in 58 (25.7%) patients. Elevated levels of troponin were 
      observed in 103 (46%) patients. Logistic regression analysis showed that 
      in-hospital mortality was associated with: coronary chest pain (0.06-0.53, OR 
      0.18), systolic blood pressure below 100 mm Hg (2.3-13.64, OR 5.61), heart rate 
      above 100 bpm (1.17-15.11, OR 4.21), the S1Q3T3 sign (1.31-6.99, OR 3.02), QR in 
      V(1) (1.60-12.32, OR 4.45), ST-segment depression in V(4)-V(6) (0.99-5.40, OR 
      2.31), ST-segment elevation in III (0.99-6.96, OR 2.64), ST-segment elevation in 
      V(1) (1.74-9.49, OR 4.07); borderline (1.51-16.07, OR 4.93), moderate 
      (1.42-17.74, OR 5.01) and severe troponin elevation (2.88-36.38, OR 10.24). In 
      patients with cTnT(+), compared to patients with normal troponin levels, the 
      following ECG changes were significantly more common: the S1Q3T3 sign (43 vs 21%, 
      p = 0.003), negative T waves in V(2)-V(4) (57 vs 27%, p = 0.0001), ST-segment 
      depression in V(4)-V(6) (40 vs 14%, p = 0.001), ST-segment elevation in III (22 
      vs 7%, p = 0.0006), V(1) and V(2) (43 vs 10%, p = 0.0001) and QR in V(1) (16 vs 
      5%, p = 0.007). CONCLUSIONS: ECG parameters are useful in predicting myocardial 
      injury and assessing prognosis in patients with APE.
FAU - Kukla, Piotr
AU  - Kukla P
AD  - Department of Internal Diseases and Cardiology, H. Klimontowicz Hospital, 
      Gorlice, Poland. kukla_piotr@poczta.onet.pl
FAU - Dlugopolski, Robert
AU  - Dlugopolski R
FAU - Krupa, Ewa
AU  - Krupa E
FAU - Furtak, Romana
AU  - Furtak R
FAU - Wrabec, Krzysztof
AU  - Wrabec K
FAU - Szelemej, Roman
AU  - Szelemej R
FAU - Mirek-Bryniarska, Ewa
AU  - Mirek-Bryniarska E
FAU - Wanczura, Piotr
AU  - Wanczura P
FAU - Jastrzebski, Marek
AU  - Jastrzebski M
FAU - Bryniarski, Leszek
AU  - Bryniarski L
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Kardiol Pol
JT  - Kardiologia polska
JID - 0376352
RN  - 0 (Biomarkers)
RN  - 0 (Troponin)
SB  - IM
CIN - Kardiol Pol. 2011;69(9):939. PMID: 21928204
MH  - Acute Disease
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers/metabolism
MH  - Electrocardiography/*methods/standards
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*complications/mortality/physiopathology
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Pulmonary Embolism/*complications/mortality/physiopathology
MH  - Regression Analysis
MH  - Troponin/*metabolism
EDAT- 2011/09/20 06:00
MHDA- 2012/01/26 06:00
CRDT- 2011/09/20 06:00
PHST- 2011/09/20 06:00 [entrez]
PHST- 2011/09/20 06:00 [pubmed]
PHST- 2012/01/26 06:00 [medline]
PST - ppublish
SO  - Kardiol Pol. 2011;69(9):933-8.