PMID- 21931574
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20111110
LR  - 20211020
IS  - 1662-6567 (Electronic)
IS  - 1662-6567 (Linking)
VI  - 3
IP  - 1
DP  - 2011 Jan
TI  - Myeloperoxidase-antineutrophil cytoplasmic antibody-negative microscopic 
      polyangiitis with pulmonary haemorrhage and IgA nephropathy.
PG  - 22-7
LID - 10.1159/000324422 [doi]
AB  - AIM: To report a case of a patient with myeloperoxidase-antineutrophil 
      cytoplasmic antibody (ANCA)-negative microscopic polyangiitis (MPA) and IgA 
      nephropathy associated with severe pulmonary haemorrhage. CASE REPORT: A 
      59-year-old man presented with ANCA-negative systemic vasculitis accompanied by 
      purpura, nephritis and pulmonary haemorrhage. A skin biopsy specimen revealed 
      pandermal leucocytoclastic vasculitis without IgA deposition and a kidney biopsy 
      showed mesangial nephritis with IgA deposition. Considering these findings, the 
      patient was diagnosed as having MPA with IgA nephropathy. DISCUSSION: In most 
      cases, MPA presents with rapidly progressive necrotizing glomerulonephritis and 
      sometimes lung haemorrhage, while IgA nephropathy is less common among MPA cases. 
      As recent research suggested that in MPA immunoglobulin deposition in the kidney 
      may be an exacerbating factor for renal dysfunction and poor prognosis, close 
      observation is required in these cases.
FAU - Endo, Yuichiro
AU  - Endo Y
AD  - Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, 
      Japan.
FAU - Minato, Haruka
AU  - Minato H
FAU - Taki, Reiko
AU  - Taki R
FAU - Kato, Mayumi
AU  - Kato M
FAU - Kore-Eda, Satoshi
AU  - Kore-Eda S
FAU - Miyachi, Yoshiki
AU  - Miyachi Y
FAU - Tanioka, Miki
AU  - Tanioka M
LA  - eng
PT  - Case Reports
DEP - 20110205
PL  - Switzerland
TA  - Case Rep Dermatol
JT  - Case reports in dermatology
JID - 101517685
PMC - PMC3175359
OTO - NOTNLM
OT  - IgA nephropathy
OT  - Microscopic polyangiitis
OT  - Pulmonary haemorrhage
EDAT- 2011/09/21 06:00
MHDA- 2011/09/21 06:01
PMCR- 2011/02/05
CRDT- 2011/09/21 06:00
PHST- 2011/09/21 06:00 [entrez]
PHST- 2011/09/21 06:00 [pubmed]
PHST- 2011/09/21 06:01 [medline]
PHST- 2011/02/05 00:00 [pmc-release]
AID - 000324422 [pii]
AID - cde0003-0022 [pii]
AID - 10.1159/000324422 [doi]
PST - ppublish
SO  - Case Rep Dermatol. 2011 Jan;3(1):22-7. doi: 10.1159/000324422. Epub 2011 Feb 5.