PMID- 21936439
OWN - NLM
STAT- MEDLINE
DCOM- 20111013
LR  - 20110922
IS  - 0890-9091 (Print)
IS  - 0890-9091 (Linking)
VI  - 25
IP  - 9
DP  - 2011 Aug
TI  - Surgical management of neuroendocrine tumors of the gastrointestinal tract.
PG  - 794-803
AB  - Neuroendocrine tumors of the pancreas (islet cell tumors) and of the luminal 
      gastrointestinal tract (carcinoids) are a heterogeneous group of epithelial 
      neoplasms that share certain common characteristics. First, they are similar 
      histologically and are difficult to distinguish under light microscopy. Second, 
      they can be associated with hypersecretory syndromes. Third, they are generally 
      slow-growing and have a better prognosis than adenocarcinomas at the same site; 
      however, they do become incurable when they progress to unresectable metastatic 
      disease. Surgery is the only curative treatment and is recommended for most 
      patients for whom cross-sectional imaging suggests that complete resection is 
      possible. This article reviews the surgical management of gastrointestinal 
      neuroendocrine tumors, including the preoperative control of hormonal symptoms, 
      extent of resection required, postoperative outcomes, and differing management 
      strategies as determined by whether the tumor has arisen sporadically or as part 
      of a familial disorder, such as multiple endocrine neoplasia type 1 (MEN1).
FAU - Huang, Lyen C
AU  - Huang LC
AD  - Department of Surgery, Stanford University School of Medicine, Stanford, 
      California 94305-5641, USA.
FAU - Poultsides, George A
AU  - Poultsides GA
FAU - Norton, Jeffrey A
AU  - Norton JA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Oncology (Williston Park)
JT  - Oncology (Williston Park, N.Y.)
JID - 8712059
SB  - IM
CIN - Oncology (Williston Park). 2011 Aug;25(9):806, 808, 810. PMID: 21936440
CIN - Oncology (Williston Park). 2011 Aug;25(9):810, 812. PMID: 21936441
MH  - Gastrointestinal Neoplasms/pathology/*surgery
MH  - Humans
MH  - Liver Neoplasms/secondary/surgery
MH  - Neuroendocrine Tumors/pathology/*surgery
MH  - Pancreatic Neoplasms/pathology/*surgery
EDAT- 2011/09/23 06:00
MHDA- 2011/10/14 06:00
CRDT- 2011/09/23 06:00
PHST- 2011/09/23 06:00 [entrez]
PHST- 2011/09/23 06:00 [pubmed]
PHST- 2011/10/14 06:00 [medline]
AID - 167773 [pii]
PST - ppublish
SO  - Oncology (Williston Park). 2011 Aug;25(9):794-803.