PMID- 21952558
OWN - NLM
STAT- MEDLINE
DCOM- 20120320
LR  - 20131121
IS  - 1477-9234 (Electronic)
IS  - 1477-9226 (Linking)
VI  - 40
IP  - 47
DP  - 2011 Dec 21
TI  - NO and O2 reactivities of synthetic functional models of nitric oxide reductase 
      and cytochrome c oxidase.
PG  - 12633-47
LID - 10.1039/c1dt10451a [doi]
AB  - Though nitric oxide reductase (NOR) and cytochrome c oxidase (CcO) have similar 
      active sites, they exhibit quite different functions. While NOR reduces NO to 
      N(2)O, CcO reduces O(2) to H(2)O. Further, CcO is reversibly inhibited by NO, the 
      substrate for NOR, and NOR is reversibly inhibited by O(2), which is the 
      substrate for CcO. Over the past decade several structural and functional models 
      of these enzymes have been reported. The mimics have been used to understand the 
      reaction mechanism of these enzymes and develop structure function correlations 
      for these active sites. This article summarizes these recent developments with 
      particular stress on the reactivities of functional mimics of CcO with NO and 
      functional mimics of NOR with O(2).
CI  - This journal is (c) The Royal Society of Chemistry 2011
FAU - Dey, Somdatta Ghosh
AU  - Dey SG
AD  - Department of Inorganic Chemistry, Indian Association for the Cultivation of 
      Science, 2A & 2B Raja S. C. Mullick Road, Kolkata, 700032, India. 
      icsgd@iacs.res.in
FAU - Dey, Abhishek
AU  - Dey A
LA  - eng
PT  - Journal Article
DEP - 20110928
PL  - England
TA  - Dalton Trans
JT  - Dalton transactions (Cambridge, England : 2003)
JID - 101176026
RN  - 31C4KY9ESH (Nitric Oxide)
RN  - EC 1.- (Oxidoreductases)
RN  - EC 1.7.2.5 (nitric-oxide reductase)
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Animals
MH  - Bacteria/enzymology
MH  - Catalytic Domain
MH  - Cattle
MH  - Electron Transport Complex IV/*metabolism
MH  - Kinetics
MH  - Models, Molecular
MH  - Nitric Oxide/*metabolism
MH  - Oxidation-Reduction
MH  - Oxidoreductases/*metabolism
MH  - Oxygen/*metabolism
MH  - Thermodynamics
EDAT- 2011/09/29 06:00
MHDA- 2012/03/21 06:00
CRDT- 2011/09/29 06:00
PHST- 2011/09/29 06:00 [entrez]
PHST- 2011/09/29 06:00 [pubmed]
PHST- 2012/03/21 06:00 [medline]
AID - 10.1039/c1dt10451a [doi]
PST - ppublish
SO  - Dalton Trans. 2011 Dec 21;40(47):12633-47. doi: 10.1039/c1dt10451a. Epub 2011 Sep 
      28.