PMID- 21957734
OWN - NLM
STAT- MEDLINE
DCOM- 20111110
LR  - 20191112
IS  - 1505-1773 (Print)
IS  - 1505-1773 (Linking)
VI  - 14
IP  - 3
DP  - 2011
TI  - Antibiotic susceptibility of methicillin-resistant and methicillin-susceptible 
      coagulase-negative staphylococci isolated from bovine mastitis.
PG  - 405-10
AB  - The aim of the present study was to evaluate the antibiotic susceptibility of 
      methicillin-susceptible (MS) and methicillin-resistant (MR) coagulase-negative 
      Staphylococcus (CNS) strains isolated from milk of cows with mastitis. The study 
      was conducted on 100 CNS strains (20 MRCNS and 80 MSCNS) isolated from milk 
      samples of 86 cows from the Lublin (Poland) region farms. Antibiotic 
      susceptibility of microorganisms was evaluated using the disc-diffusion method on 
      the Mueller-Hinton agar according to the guidelines of the National Committee for 
      Clinical Laboratory Standards (NCCLS). The highest efficacy against MSCNS was 
      demonstrated for cephalosporin antibiotics, i.e. cefacetril (91.3%), ceftiofur 
      (67.5%), cefoperazone (66.3%) and cephalexin (60.0% of susceptible MSCNS 
      strains). Moreover, a high percentage of vancomycin-susceptible strains was 
      demonstrated (83.8%). The activity of combination of amoxicillin with clavulanic 
      acid and gentamicin was found weaker (63.8% and 61.3% of susceptible strains, 
      respectively). About 50.0% of MSCNS were susceptible to erythromycin, 
      enrofloxacine and amoxicillin. A large proportion of CNS was resistant to 
      neomycin, penicillin, tetracycline, streptomycin, lincomycin and ampicillin 
      (28.8%, 30.0%, 31.3%, 31.3%, 33.8% and 33.8% of susceptible strains, 
      respectively). The highest percentage of MRCNS was susceptible to vancomycin 
      (75.0%), erythromycin (65.0%) and streptomycin (50.0%). Their susceptibility to 
      enrofloxacine (35.0%) as well as gentamicin and tetracycline (30.0%) was markedly 
      lower. The lowest activity was found for lincomycin and neomycin (20.0% of 
      susceptible MRCNS strains, each).
FAU - Bochniarz, M
AU  - Bochniarz M
AD  - Department and Clinic of Animal Reproduction, Faculty of Veterinary Medicine, 
      University of Life Sciences, Gleboka 30, 20-612 Lublin, Poland. 
      mariolabochniarz@interia.pl
FAU - Wawron, W
AU  - Wawron W
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Pol J Vet Sci
JT  - Polish journal of veterinary sciences
JID - 101125473
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Animals
MH  - Anti-Bacterial Agents/*pharmacology
MH  - Cattle
MH  - *Drug Resistance, Multiple, Bacterial
MH  - Female
MH  - Mastitis, Bovine/*microbiology
MH  - Methicillin-Resistant Staphylococcus aureus/*drug effects
MH  - Staphylococcal Infections/microbiology/*veterinary
EDAT- 2011/10/01 06:00
MHDA- 2011/11/11 06:00
CRDT- 2011/10/01 06:00
PHST- 2011/10/01 06:00 [entrez]
PHST- 2011/10/01 06:00 [pubmed]
PHST- 2011/11/11 06:00 [medline]
AID - 10.2478/v10181-011-0060-5 [doi]
PST - ppublish
SO  - Pol J Vet Sci. 2011;14(3):405-10. doi: 10.2478/v10181-011-0060-5.