PMID- 21958371
OWN - NLM
STAT- MEDLINE
DCOM- 20120208
LR  - 20221207
IS  - 1557-8976 (Electronic)
IS  - 0882-8245 (Linking)
VI  - 24
IP  - 5
DP  - 2011 Oct
TI  - Human-leukocyte antigen class I Cw 1502 and class II DR 0301 genotypes are 
      associated with resistance to severe acute respiratory syndrome (SARS) infection.
PG  - 421-6
LID - 10.1089/vim.2011.0024 [doi]
AB  - One-hundred and thirty confirmed cases of severe acute respiratory syndrome 
      (SARS) were recruited to evaluate their anti-SARS-coronavirus (CoV) antibody 
      status and human leukocyte antigen (HLA) types in September 2006, 3 y after the 
      SARS outbreaks in Taiwan. Western blot assay showed that 6.9% of participants 
      still had anti-spike and anti-nucleocapside antibodies. A case-control study of 
      the association of HLA with SARS revealed that the HLA-Cw1502 and DR0301 alleles 
      conferred resistance against SARS infection (p<0.05).
FAU - Wang, Sheng-Fan
AU  - Wang SF
AD  - Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
FAU - Chen, Kuan-Hsuan
AU  - Chen KH
FAU - Chen, Marcelo
AU  - Chen M
FAU - Li, Wen-Yi
AU  - Li WY
FAU - Chen, Yen-Ju
AU  - Chen YJ
FAU - Tsao, Ching-Han
AU  - Tsao CH
FAU - Yen, Muh-yong
AU  - Yen MY
FAU - Huang, Jason C
AU  - Huang JC
FAU - Chen, Yi-Ming Arthur
AU  - Chen YM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110929
PL  - United States
TA  - Viral Immunol
JT  - Viral immunology
JID - 8801552
RN  - 0 (Antibodies, Neutralizing)
RN  - 0 (Antibodies, Viral)
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-DR0301 antigen)
RN  - 0 (HLA-DR3 Antigen)
SB  - IM
MH  - Adult
MH  - Antibodies, Neutralizing/blood
MH  - Antibodies, Viral/*blood
MH  - Asian People/*genetics
MH  - Case-Control Studies
MH  - Disease Resistance/*genetics/immunology
MH  - Female
MH  - Genotype
MH  - HLA-C Antigens/*genetics
MH  - HLA-DR3 Antigen/*genetics
MH  - Histocompatibility Testing
MH  - Humans
MH  - Male
MH  - Severe acute respiratory syndrome-related coronavirus/immunology/pathogenicity
MH  - Severe Acute Respiratory Syndrome/epidemiology/*genetics/immunology
MH  - Taiwan/epidemiology
EDAT- 2011/10/01 06:00
MHDA- 2012/02/09 06:00
CRDT- 2011/10/01 06:00
PHST- 2011/10/01 06:00 [entrez]
PHST- 2011/10/01 06:00 [pubmed]
PHST- 2012/02/09 06:00 [medline]
AID - 10.1089/vim.2011.0024 [doi]
PST - ppublish
SO  - Viral Immunol. 2011 Oct;24(5):421-6. doi: 10.1089/vim.2011.0024. Epub 2011 Sep 
      29.