PMID- 2195961 OWN - NLM STAT- MEDLINE DCOM- 19900813 LR - 20170214 IS - 0003-4894 (Print) IS - 0003-4894 (Linking) VI - 99 IP - 7 Pt 1 DP - 1990 Jul TI - Immunoglobulin E and circulating immune complexes in endolymphatic hydrops. PG - 535-8 AB - Levels of circulating immune complexes (CICs) in 59 patients with Meniere's disease and total serum immunoglobulin E (IgE) levels in a subgroup of 42 of the 59 were determined quantitatively for possible abnormalities of humoral immunity. Significant differences in average IgE levels between the 42 patients with Meniere's disease and 18 normal control subjects were not determined; however, five (11.9%) of the 42 patients were found to have obviously raised IgE levels. Elevated CIC levels were found in 19 (32.2%) of the 59 patients with Meniere's disease and in one (2.3%) of the 43 control subjects. This difference was statistically significant. The possible mechanisms of immune-mediated endolymphatic hydrops are discussed. FAU - Hsu, L AU - Hsu L AD - Beijing Institute of Otorhinolaryngology, People's Republic of China. FAU - Zhu, X N AU - Zhu XN FAU - Zhao, Y S AU - Zhao YS LA - eng PT - Journal Article PT - Review PL - United States TA - Ann Otol Rhinol Laryngol JT - The Annals of otology, rhinology, and laryngology JID - 0407300 RN - 0 (Antigen-Antibody Complex) RN - 0 (Immunoglobulin G) SB - IM CIN - Ann Otol Rhinol Laryngol. 1991 May;100(5 Pt 1):431-2. PMID: 2024904 MH - Adult MH - Aged MH - Antigen-Antibody Complex/*analysis MH - Audiometry, Pure-Tone MH - Edema/etiology/*immunology MH - *Endolymphatic Duct MH - Female MH - Humans MH - Hypersensitivity/complications/*immunology MH - Immunoglobulin G/*analysis MH - Male MH - Meniere Disease/complications/*immunology/pathology MH - Middle Aged MH - Vestibular Diseases/etiology/*immunology MH - *Vestibule, Labyrinth RF - 24 EDAT- 1990/07/01 00:00 MHDA- 1990/07/01 00:01 CRDT- 1990/07/01 00:00 PHST- 1990/07/01 00:00 [pubmed] PHST- 1990/07/01 00:01 [medline] PHST- 1990/07/01 00:00 [entrez] AID - 10.1177/000348949009900707 [doi] PST - ppublish SO - Ann Otol Rhinol Laryngol. 1990 Jul;99(7 Pt 1):535-8. doi: 10.1177/000348949009900707.