PMID- 21962089
OWN - NLM
STAT- MEDLINE
DCOM- 20111129
LR  - 20151119
IS  - 1534-4436 (Electronic)
IS  - 1081-1206 (Linking)
VI  - 107
IP  - 4
DP  - 2011 Oct
TI  - Can early household exposure influence the development of rhinitis symptoms in 
      infancy? Findings from the PARIS birth cohort.
PG  - 303-9
LID - 10.1016/j.anai.2011.07.004 [doi]
AB  - BACKGROUND: Allergic rhinitis (AR) has become the most prevalent chronic allergic 
      disorder in childhood, and the role of environment has been questioned, 
      particularly in early life. OBJECTIVE: To investigate the risk factors for 
      rhinitis symptoms in infants included in the PARIS (Pollution and Asthma Risk: an 
      Infant Study) birth cohort. METHODS: Infants were invited to participate at age 
      18 months in a health examination conducted by a pediatrician. Allergic rhinitis 
      was defined as the presence of rhinitis symptoms (runny nose, blocked nose, 
      sneezing in the absence of a cold) combined with biological atopy (elevated total 
      immunoglobulin E [IgE], specific IgE, or eosinophilia) and nonallergic rhinitis 
      (NAR) as symptoms without biological atopy. Information about indoor exposures 
      and lifestyle was collected during a telephone interview when the child was 1 
      month of age. Risk factors for AR and NAR were studied by using a polytomous 
      regression model. RESULTS: The prevalence of AR and NAR was 70/1,850 (3.8%) and 
      99/1,850 (5.4%), respectively. Allergic rhinitis and NAR did not share similar 
      risk factors. Male sex (odds ratio [OR] = 1.99 [1.19-3.32]), parental history of 
      AR (OR = 1.89 [1.16-3.08]), low socioeconomic class (OR = 2.23 [1.05-4.72] for 
      low vs high level), and the presence of cockroaches in the home (OR = 3.15 
      [1.67-5.96]) were risk factors for AR. Conversely, the presence of particle-board 
      furniture less than 12 months old in the child's bedroom was associated with an 
      increased risk of NAR (OR = 1.87 [1.21-2.90]). CONCLUSIONS: This study should 
      raise awareness about the impact of indoor exposures, particularly with regard to 
      cockroaches and particle-board furniture, because they could influence the 
      occurrence of noninfectious rhinitis.
CI  - Copyright (c) 2011 American College of Allergy, Asthma & Immunology. Published by 
      Elsevier Inc. All rights reserved.
FAU - Herr, Marie
AU  - Herr M
AD  - Universite Paris Descartes, Laboratoire Sante Publique et Environnement, Paris, 
      France.
FAU - Nikasinovic, Lydia
AU  - Nikasinovic L
FAU - Foucault, Christophe
AU  - Foucault C
FAU - Le Marec, Anne-Marie
AU  - Le Marec AM
FAU - Giordanella, Jean-Pierre
AU  - Giordanella JP
FAU - Just, Jocelyne
AU  - Just J
FAU - Momas, Isabelle
AU  - Momas I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110805
PL  - United States
TA  - Ann Allergy Asthma Immunol
JT  - Annals of allergy, asthma & immunology : official publication of the American 
      College of Allergy, Asthma, & Immunology
JID - 9503580
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Chi-Square Distribution
MH  - Cohort Studies
MH  - Eosinophilia/immunology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Infant
MH  - Male
MH  - Paris/epidemiology
MH  - Prevalence
MH  - Rhinitis, Allergic, Perennial/*epidemiology/etiology/*immunology
MH  - Risk Factors
MH  - Surveys and Questionnaires
EDAT- 2011/10/04 06:00
MHDA- 2011/12/13 00:00
CRDT- 2011/10/04 06:00
PHST- 2011/03/22 00:00 [received]
PHST- 2011/06/09 00:00 [revised]
PHST- 2011/07/11 00:00 [accepted]
PHST- 2011/10/04 06:00 [entrez]
PHST- 2011/10/04 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
AID - S1081-1206(11)00515-1 [pii]
AID - 10.1016/j.anai.2011.07.004 [doi]
PST - ppublish
SO  - Ann Allergy Asthma Immunol. 2011 Oct;107(4):303-9. doi: 
      10.1016/j.anai.2011.07.004. Epub 2011 Aug 5.