PMID- 21972108 OWN - NLM STAT- MEDLINE DCOM- 20120229 LR - 20211020 IS - 1522-2586 (Electronic) IS - 1053-1807 (Print) IS - 1053-1807 (Linking) VI - 34 IP - 6 DP - 2011 Dec TI - Three-dimensional late gadolinium enhancement imaging of the left atrium with a hybrid radial acquisition and compressed sensing. PG - 1465-71 LID - 10.1002/jmri.22808 [doi] AB - PURPOSE: To develop and test a hybrid radial (stack of stars) acquisition and compressed sensing reconstruction for efficient late gadolinium enhancement (LGE) imaging of the left atrium. MATERIALS AND METHODS: Two hybrid radial acquisition schemes, kx-ky-first and kz-first, are tested using the signal equation for an inversion recovery sequence with simulated data. Undersampled data reconstructions are then performed using a compressed sensing approach with a three-dimensional total variation constraint. The data acquisition and reconstruction framework is tested on five atrial fibrillation patients after treatment by radio-frequency ablation. The hybrid radial data are acquired with free breathing without respiratory navigation. RESULTS: The kz-first radial acquisition gave improved image quality as compared to a kx-ky-first scheme. Compressed sensing reconstructions improved the overall quality of undersampled radial LGE images. An image quality metric that takes into account the signal, noise, artifact, and blur for the radial images was 35% (+/-17%) higher than the corresponding Cartesian acquisitions. Total acquisition time for 36 slices with 1.25 x 1.25 x 2.5 mm(3) resolution was under 3 min for the proposed scheme. CONCLUSION: Hybrid radial LGE imaging of the LA with compressed sensing is a promising approach for obtaining images efficiently and offers more robust image quality than Cartesian acquisitions that were acquired without a respiratory navigator signal. CI - Copyright (c) 2011 Wiley Periodicals, Inc. FAU - Adluru, Ganesh AU - Adluru G AD - UCAIR, Department of Radiology, University of Utah, Salt Lake City, Utah, USA; CARMA, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA. gadluru@gmail.com FAU - Chen, Liyong AU - Chen L FAU - Kim, Seong-Eun AU - Kim SE FAU - Burgon, Nathan AU - Burgon N FAU - Kholmovski, Eugene G AU - Kholmovski EG FAU - Marrouche, Nassir F AU - Marrouche NF FAU - Dibella, Edward V R AU - Dibella EV LA - eng GR - R21 HL110059/HL/NHLBI NIH HHS/United States GR - R21 HL110059-01/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20111003 PL - United States TA - J Magn Reson Imaging JT - Journal of magnetic resonance imaging : JMRI JID - 9105850 RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Atrial Fibrillation/surgery MH - Catheter Ablation MH - *Gadolinium MH - Heart Atria/*anatomy & histology MH - Humans MH - Image Enhancement MH - Magnetic Resonance Imaging/*methods PMC - PMC3324824 MID - NIHMS367050 EDAT- 2011/10/06 06:00 MHDA- 2012/03/01 06:00 PMCR- 2012/12/01 CRDT- 2011/10/06 06:00 PHST- 2010/12/16 00:00 [received] PHST- 2011/08/12 00:00 [accepted] PHST- 2011/10/06 06:00 [entrez] PHST- 2011/10/06 06:00 [pubmed] PHST- 2012/03/01 06:00 [medline] PHST- 2012/12/01 00:00 [pmc-release] AID - 10.1002/jmri.22808 [doi] PST - ppublish SO - J Magn Reson Imaging. 2011 Dec;34(6):1465-71. doi: 10.1002/jmri.22808. Epub 2011 Oct 3.