PMID- 21972259
OWN - NLM
STAT- MEDLINE
DCOM- 20120712
LR  - 20240317
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Print)
IS  - 1040-4651 (Linking)
VI  - 23
IP  - 10
DP  - 2011 Oct
TI  - A versatile monosaccharide transporter that operates in the arbuscular 
      mycorrhizal fungus Glomus sp is crucial for the symbiotic relationship with 
      plants.
PG  - 3812-23
LID - 10.1105/tpc.111.089813 [doi]
AB  - For more than 400 million years, plants have maintained a mutualistic symbiosis 
      with arbuscular mycorrhizal (AM) fungi. This evolutionary success can be traced 
      to the role of these fungi in providing plants with mineral nutrients, 
      particularly phosphate. In return, photosynthates are given to the fungus, which 
      support its obligate biotrophic lifestyle. Although the mechanisms involved in 
      phosphate transfer have been extensively studied, less is known about the 
      reciprocal transfer of carbon. Here, we present the high-affinity Monosaccharide 
      Transporter2 (MST2) from Glomus sp with a broad substrate spectrum that functions 
      at several symbiotic root locations. Plant cell wall sugars can efficiently 
      outcompete the Glc uptake capacity of MST2, suggesting they can serve as 
      alternative carbon sources. MST2 expression closely correlates with that of the 
      mycorrhiza-specific Phosphate Transporter4 (PT4). Furthermore, reduction of MST2 
      expression using host-induced gene silencing resulted in impaired mycorrhiza 
      formation, malformed arbuscules, and reduced PT4 expression. These findings 
      highlight the symbiotic role of MST2 and support the hypothesis that the exchange 
      of carbon for phosphate is tightly linked. Unexpectedly, we found that the 
      external mycelium of AM fungi is able to take up sugars in a proton-dependent 
      manner. These results imply that the sugar uptake system operating in this 
      symbiosis is more complex than previously anticipated.
FAU - Helber, Nicole
AU  - Helber N
AD  - Plant-Microbial Interactions Group, Karlsruhe Institute of Technology, 
      Hertzstrasse 16, D-76187 Karlsruhe, Germany.
FAU - Wippel, Kathrin
AU  - Wippel K
FAU - Sauer, Norbert
AU  - Sauer N
FAU - Schaarschmidt, Sara
AU  - Schaarschmidt S
FAU - Hause, Bettina
AU  - Hause B
FAU - Requena, Natalia
AU  - Requena N
LA  - eng
SI  - GENBANK/HM143864
SI  - GENBANK/HQ848964
SI  - GENBANK/HQ848965
SI  - GENBANK/HQ848966
SI  - GENBANK/JK511416
SI  - GENBANK/JK511417
SI  - GENBANK/JK511418
SI  - GENBANK/JN686742
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111004
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Fungal Proteins)
RN  - 0 (Monosaccharide Transport Proteins)
RN  - 0 (Phosphates)
RN  - 0 (Protons)
RN  - A1TA934AKO (Xylose)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
CIN - Plant Cell. 2011 Oct;23(10):3561. PMID: 22003078
MH  - Base Sequence
MH  - Biological Transport
MH  - Fungal Proteins/genetics/metabolism
MH  - Gene Library
MH  - Glomeromycota/genetics/*physiology/ultrastructure
MH  - Glucose/metabolism
MH  - Homeostasis
MH  - Medicago truncatula/*microbiology/physiology
MH  - Molecular Sequence Data
MH  - Monosaccharide Transport Proteins/genetics/*metabolism
MH  - Mycelium/metabolism
MH  - Mycorrhizae/genetics/*physiology/ultrastructure
MH  - Phosphates/metabolism
MH  - Phylogeny
MH  - Plant Roots/microbiology
MH  - Protons
MH  - Sequence Analysis, DNA
MH  - Signal Transduction
MH  - Substrate Specificity
MH  - Symbiosis/*physiology
MH  - Xylose/metabolism
PMC - PMC3229151
EDAT- 2011/10/06 06:00
MHDA- 2012/07/13 06:00
PMCR- 2012/10/01
CRDT- 2011/10/06 06:00
PHST- 2011/10/06 06:00 [entrez]
PHST- 2011/10/06 06:00 [pubmed]
PHST- 2012/07/13 06:00 [medline]
PHST- 2012/10/01 00:00 [pmc-release]
AID - tpc.111.089813 [pii]
AID - 089813 [pii]
AID - 10.1105/tpc.111.089813 [doi]
PST - ppublish
SO  - Plant Cell. 2011 Oct;23(10):3812-23. doi: 10.1105/tpc.111.089813. Epub 2011 Oct 
      4.