PMID- 21972664 OWN - NLM STAT- MEDLINE DCOM- 20111025 LR - 20111006 IS - 0254-9395 (Print) IS - 0254-9395 (Linking) VI - 83 IP - 2 DP - 2011 Apr-Jun TI - Type 2 lepra reaction with HIV1 co-infection: a case report with interesting management implications. PG - 103-6 AB - A patient co-infected with leprosy and Human Immunodeficiency Virus (HIV)-type 1 who developed type 2 lepra reaction in the absence of antiretroviral therapy is presented. The reaction responded only after initiating anti retroviral therapy (ART) despite normal CD4+ counts. The present report suggests that type 2 reactions in leprosy and HIV co-infected patients may not always be the typical manifestation of immune reconstitution inflammatory syndrome (IRIS) and stresses the importance of considering concomitant HIV infection in refractory lepra reactions. Extensive research is required into the manifestations of HIV in leprosy patients. FAU - Sachdeva, S AU - Sachdeva S AD - Department of Dematology, Venereology and Leprology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh-202 002, India. sandeepsemail@rediffmail.com FAU - Amin, S S AU - Amin SS FAU - Qaisar, S AU - Qaisar S LA - eng PT - Case Reports PT - Journal Article PL - India TA - Indian J Lepr JT - Indian journal of leprosy JID - 8409173 RN - 0 (Anti-Retroviral Agents) RN - 0 (Leprostatic Agents) SB - IM MH - AIDS-Related Opportunistic Infections/*chemically induced/immunology MH - Adult MH - Anti-Retroviral Agents/therapeutic use MH - CD4 Lymphocyte Count MH - Erythema Nodosum/*chemically induced/diagnosis MH - Female MH - HIV Infections/complications/drug therapy/*immunology MH - *HIV-1 MH - Humans MH - Leprostatic Agents/therapeutic use MH - Leprosy, Lepromatous/*chemically induced/diagnosis MH - Treatment Outcome EDAT- 2011/10/07 06:00 MHDA- 2011/10/26 06:00 CRDT- 2011/10/07 06:00 PHST- 2011/10/07 06:00 [entrez] PHST- 2011/10/07 06:00 [pubmed] PHST- 2011/10/26 06:00 [medline] PST - ppublish SO - Indian J Lepr. 2011 Apr-Jun;83(2):103-6.