PMID- 21973131
OWN - NLM
STAT- MEDLINE
DCOM- 20120208
LR  - 20111006
IS  - 1364-6893 (Electronic)
IS  - 0144-3615 (Linking)
VI  - 31
IP  - 7
DP  - 2011 Oct
TI  - Severe heart disease complicating pregnancy does not preclude a favourable 
      pregnancy outcome: 15 years' experience in a single centre.
PG  - 597-602
LID - 10.3109/01443615.2011.603064 [doi]
AB  - Heart disease (HD) in pregnancy remains a major cause of non-obstetric maternal 
      and neonatal mortality and morbidity. This study describes the outcome in 164 
      pregnant women with HD (158 deliveries in women in New York Heart Association 
      (NYHA) Classes 1 and 2; 17 in NYHA Classes 3 and 4) who received good antenatal 
      care and benefitted from a specific protocol and experience of a dedicated staff. 
      There were no maternal or neonatal deaths; 46 women were diagnosed peripartum. 
      Based on a sub-division into NYHA categories, and when sub-divided by HD, there 
      were no statistically significant differences between groups with regard to 
      maternal age, gestational age at admission or at delivery, birth weight, 5 min 
      Apgar scores, mode of delivery (caesarean delivery), senior 
      obstetric/anaesthesiology staff in attendance or delivery during day/working 
      hours. There was a higher incidence of pre-term deliveries in women with 
      rheumatic heart disease and Marfan syndrome (p = 0.06) relative to others. Babies 
      of women with coronary heart disease had prolonged postpartum course in the NICU 
      (p = 0.0001) and longer total hospital stays for the mother. In conclusion, 
      well-managed, motivated mothers with HD who benefit from comprehensive antenatal 
      care, and are managed primarily by their obstetric and anaesthesia teams, can 
      aspire to a good outcome for themselves and their babies.
FAU - Michaelson-Cohen, R
AU  - Michaelson-Cohen R
AD  - Department Obstetrics and Gynecology, Hebrew University of Jerusalem, Shaare 
      Zedek Medical Centre, Jerusalem, Israel.
FAU - Elstein, D
AU  - Elstein D
FAU - Ioscovich, A
AU  - Ioscovich A
FAU - Armon, S
AU  - Armon S
FAU - Schimmel, M S
AU  - Schimmel MS
FAU - Butnaru, A
AU  - Butnaru A
FAU - Samueloff, A
AU  - Samueloff A
FAU - Grisaru-Granovsky, S
AU  - Grisaru-Granovsky S
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Obstet Gynaecol
JT  - Journal of obstetrics and gynaecology : the journal of the Institute of 
      Obstetrics and Gynaecology
JID - 8309140
SB  - IM
MH  - Adult
MH  - Birth Weight
MH  - Coronary Disease/complications
MH  - Delivery, Obstetric/methods
MH  - Female
MH  - Gestational Age
MH  - Heart Diseases/*complications/therapy
MH  - Humans
MH  - Intensive Care, Neonatal/statistics & numerical data
MH  - Male
MH  - Marfan Syndrome/complications
MH  - Maternal Age
MH  - Pregnancy
MH  - *Pregnancy Complications, Cardiovascular
MH  - *Pregnancy Outcome
MH  - Premature Birth/epidemiology
MH  - Prenatal Care
MH  - Prospective Studies
MH  - Rheumatic Heart Disease/complications
EDAT- 2011/10/07 06:00
MHDA- 2012/02/09 06:00
CRDT- 2011/10/07 06:00
PHST- 2011/10/07 06:00 [entrez]
PHST- 2011/10/07 06:00 [pubmed]
PHST- 2012/02/09 06:00 [medline]
AID - 10.3109/01443615.2011.603064 [doi]
PST - ppublish
SO  - J Obstet Gynaecol. 2011 Oct;31(7):597-602. doi: 10.3109/01443615.2011.603064.